... of expression in those cell types. Together, our results demonstrate the active role of ECM remodeling in regulating tissue homeostasis and regeneration in the planarian Schmidtea mediterranea . This article has an associated First Person interview with one of the co-first authors of the paper...

... Tumor microenvironment Cancer cell invasion ECM remodeling Mesenchymal stem cells Senescence Cell motility National Science Foundation 10.13039/100000001 1825174 HL134625 National Institutes of Health 10.13039/100000002 P30 GM110750 Mesenchymal stem cells (MSCs...

... of Biologists Limited 2007 2007 RECK MMP ECM remodeling Tissue morphogenesis Chondrogenesis The extracellular matrix (ECM) confers mechanical strength to the tissue and provides microenvironment and inductive cues essential for proper cell proliferation, migration and differentiation. The ECM...

... differentiation proceeds through three distinct stages. During elongation, the MMP-dependent ECM remodeling that is critical for the successive fusion step occurs. Time course of MMP-2, MT1-MMP and TIMP-2 expression supports the idea that MMPs are active in the elongation stage. Blocking of MMP activities...