... of expression in those cell types. Together, our results demonstrate the active role of ECM remodeling in regulating tissue homeostasis and regeneration in the planarian Schmidtea mediterranea . This article has an associated First Person interview with one of the co-first authors of the paper...

... population of MSCs can synergistically combine the invading properties of pre-senescent MSCs and SASP/ECM-remodeling properties of senescent MSCs to facilitate BCC invasion. This is significant because senescent MSCs are likely a small population of stromal cells in vivo . However, senescent MSCs can...

... is associated with later, consolidation steps or ECM accumulation. The GPI-mediated membrane anchoring makes RECK unique among endogenous MMP regulators and particularly suitable for a task that requires delicate and dynamic regulation of pericellular ECM remodeling. In our previous study using...

... © The Company of Biologists Limited 2006 2006 MT1-MMP ECM remodeling Myogenesis Myopathy Concomitant with the cellular genetic program are dramatic changes in cell morphology. Under in vitro culture conditions, the proliferating myoblast morphology resembles that of fibroblasts. Once...