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Keywords: E47
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Journal Articles

The class I bHLH factors E2-2A and E2-2B regulate EMT

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Verónica R. Sobrado, Gema Moreno-Bueno, Eva Cubillo, Liam J. Holt, M. Angela Nieto, Francisco Portillo, Amparo Cano
Journal: Journal of Cell Science
J Cell Sci (2009) 122 (7): 1014–1024.
https://doi.org/10.1242/jcs.028241
Published: 1 April 2009
... EMT when overexpressed in MDCK cells but without affecting the tumorigenic properties of parental cells, in contrast to other EMT inducers, such as Snail1 or class I bHLH E47. E-cadherin repression mediated by E2-2 is indirect and independent of proximal E-boxes of the promoter. Knockdown studies...
View articletitled, The class I bHLH factors E2-2A and E2-2B regulate EMT
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Includes: Supplementary data
Journal Articles

Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo

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Hector Peinado, Faustino Marin, Eva Cubillo, Hans-Juergen Stark, Norbert Fusenig, M. Angela Nieto, Amparo Cano
Journal: Journal of Cell Science
J Cell Sci (2004) 117 (13): 2827–2839.
https://doi.org/10.1242/jcs.01145
Published: 1 June 2004
...Hector Peinado; Faustino Marin; Eva Cubillo; Hans-Juergen Stark; Norbert Fusenig; M. Angela Nieto; Amparo Cano The transcription factors Snail and E47 are direct repressors of E-cadherin , with both inducing a full epithelial-mesenchymal transition and invasive behaviour in vitro when expressed...
View articletitled, Snail and E47 repressors of E-cadherin induce distinct invasive and angiogenic properties in vivo
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