1-20 of 39
Keywords: Dynamin
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci (2020) 133 (4): jcs236877.
Published: 24 February 2020
... in abnormal cluster morphology and disrupted endocytosis. Podocyte Nephrin Phosphotyrosine Nck Dynamin Clustering * Present address: Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, ON, K1N 6N5, Canada. Organization of plasma membrane signaling...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (21): jcs234955.
Published: 06 November 2019
...-in cell lines. The power of knocksideways is that it allows investigators to rapidly switch the protein from an active to an inactive state. We show that dongles allow for effective knocksideways of GFP-tagged proteins in genome-edited human cells. However, we discovered that nanobody binding to dynamin-2...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (1): jcs211755.
Published: 04 January 2018
... transporter LAT1–4F2hc (also known as SLC7A5–SLC3A2) and potentially via endocytosis. Here, we investigated the contribution of the different routes of Leu entry into cells to mTORC1 activation using pharmacological inhibitors and cells that lack LAT1 or dynamin-1, -2 and -3. Our results show that LAT1...
Includes: Supplementary data
Journal Articles
In collection:
Mitochondria
J Cell Sci (2017) 130 (18): 2953–2960.
Published: 15 September 2017
..., including quality control, mitochondrial (mt)DNA inheritance, transport and cell death. However, unlike bacterial fission, which uses a dynamin-related protein to constrict the membrane at its inner face, mitochondria use dynamin and dynamin-related proteins to constrict the outer membrane from...
Journal Articles
In collection:
Imaging
J Cell Sci (2017) 130 (15): 2591–2605.
Published: 01 August 2017
..., live-cell imaging and correlative spinning-disk microscopy and transmission electron microscopy assays we provide the first in-depth high-resolution characterisation of this process. We provide a model of compensatory endocytosis based on rapid clathrin- and dynamin-mediated retrieval. Inhibition...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (12): 2354–2367.
Published: 15 June 2016
.... Published by The Company of Biologists Ltd 2016 Highlighted Article: EHD proteins play regulatory functions in the endocytic pathway. We reveal that D. discoideum EHD interacts with Dynamin and controls intraphagosomal proteolysis and pH dynamics during phagosome maturation. EHD Dynamin D...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (12): 2229–2235.
Published: 15 June 2015
... with the pleckstrin homology (PH) domain of the endocytic protein dynamin 1. By using cell-attached capacitance recordings with millisecond time resolution to monitor clathrin-mediated endocytosis of single vesicles in neuroendocrine chromaffin cells, we find that loss of this interaction prolongs the lifetime...
Journal Articles
J Cell Sci (2015) 128 (4): 645–655.
Published: 15 February 2015
... the retromer, the dynamin-like Vps1, and the Rab7 GTPase Ypt7. Retromer and Vps1 leave the vacuole together with the cargo, whereas Ypt7 stays behind, in agreement with its regulatory function. Recycled cargo then accumulates at endosomes and later at the Golgi, implying consecutive sorting steps to the final...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (22): 5305–5312.
Published: 15 November 2013
...Ryan J. Park; Hongying Shen; Lijuan Liu; Xinran Liu; Shawn M. Ferguson; Pietro De Camilli Summary Dynamin, which is encoded by three genes in mammals, is a GTPase implicated in endocytic membrane fission. Dynamin 1 and 3 are predominantly expressed in brain, whereas dynamin 2 is ubiquitously...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (13): 2773–2784.
Published: 01 July 2013
...Joshua S. Chappie; Fred Dyda Summary Dynamin is a large multidomain GTPase that assembles into helical arrays around the necks of deeply invaginated clathrin-coated pits and catalyzes membrane fission during the final stages of endocytosis. Although it is well established that the function...
Journal Articles
J Cell Sci (2013) 126 (12): 2607–2616.
Published: 15 June 2013
... annular gap junction vesicles are formed. These vesicles undergo fission, but the molecular machinery needed for these fissions has not been described. The mechanoenzyme dynamin has been previously demonstrated to play a role in gap junction plaque internalization. To investigate the role of dynamin...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (1): 133–143.
Published: 01 January 2011
... at the necks of clathrin-coated pits (CCPs) during activity in lamprey synapses. Endophilin and dynamin colocalize at the base of the clathrin coat. Protein spirals composed of these proteins on lipid tubes in vitro have a pitch similar to the one observed at necks of CCPs in living synapses, and lipid tubules...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (24): 4240–4250.
Published: 15 December 2010
...Claudia Krag; Emily Kim Malmberg; Anna Elisabetta Salcini Increasing evidence indicates that cellular uptake of several molecules can occur independently of functional dynamin, but the molecular players that regulate dynamin-independent endocytosis and the subsequent trafficking steps are still...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (20): 3496–3506.
Published: 15 October 2010
...Iwona I. Smaczynska-de Rooij; Ellen G. Allwood; Soheil Aghamohammadzadeh; Ewald H. Hettema; Martin W. Goldberg; Kathryn R. Ayscough Dynamins are a conserved family of proteins involved in membrane fusion and fission. Although mammalian dynamins are known to be involved in several membrane...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2010) 123 (17): 2931–2942.
Published: 01 September 2010
... the characterization of a number of endocytic proteins that control ligand endocytosis, including dynamin, Epsin, Rab11, Arfophilin (Nuclear Fallout) and auxilin (for a review, see Brou, 2009 ), the precise role of endocytosis in the activation process remains to be established. Two principal, but not mutually...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (10): 1742–1750.
Published: 15 May 2010
... and SNX9 are expressed together in most cell lines, but to a different extent. Like SNX9, SNX18 interacts with dynamin and stimulates the basal GTPase activity of dynamin. It also interacts with neuronal Wiskott-Aldrich syndrome protein (N-WASP) and synaptojanin, as does SNX9. SNX18 and SNX9 can form...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (14): 2331–2336.
Published: 15 July 2009
... and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER. J. Cell Biol. 173 , 521 -532. Koch, A., Schneider, G., Luers, G. H. and Schrader, M. ( 2004 ). Peroxisome elongation and constriction but not fission can occur independently of dynamin-like protein 1. J...
Journal Articles
J Cell Sci (2009) 122 (11): 1713–1721.
Published: 01 June 2009
..., R. ( 2003 ). Functional inactivation of a transcriptional corepressor by a signaling kinase. Nat. Struct. Biol. 10 , 622 -628. Bashkirov, P. V., Akimov, S. A., Evseev, A. I., Schmid, S. L., Zimmerberg, J. and Frolov, V. A. ( 2008 ). GTPase cycle of dynamin is coupled to membrane squeeze...
Journal Articles
J Cell Sci (2009) 122 (1): 5–11.
Published: 01 January 2009
...Richard Lundmark; Sven R. Carlsson The sorting nexin SNX9 has, in the past few years, been singled out as an important protein that participates in fundamental cellular activities. SNX9 binds strongly to dynamin and is partly responsible for the recruitment of this GTPase to sites of endocytosis...
Journal Articles
J Cell Sci (2008) 121 (9): 1495–1505.
Published: 01 May 2008
...-family proteins act as individual entities in cells. Their SH3 domains displayed a high selectivity for dynamin 2, and the PX-BAR units had the capacity to tubulate membranes when expressed in HeLa cells. As previously described for the PX-BAR domain of SNX9 (SNX9-PX-BAR), purified SNX18-PX-BAR caused...
Includes: Supplementary data