...Marielle Saclier; Sabrina Ben Larbi; Ha My Ly; Eugénie Moulin; Rémi Mounier; Bénédicte Chazaud; Gaëtan Juban ABSTRACT Duchenne muscular dystrophy is a genetic muscle disease characterized by chronic inflammation and fibrosis mediated by a pro-fibrotic macrophage population expressing pro...

...Dejia Li; Akshay Bareja; Luke Judge; Yongping Yue; Yi Lai; Rebecca Fairclough; Kay E. Davies; Jeffrey S. Chamberlain; Dongsheng Duan Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by dystrophin deficiency. In normal muscle, dystrophin helps maintain sarcolemmal stability...

...Othon L. Gervásio; Nicholas P. Whitehead; Ella W. Yeung; William D. Phillips; David G. Allen Transient receptor potential canonical 1 (TRPC1), a widely expressed calcium (Ca 2+ )-permeable channel, is potentially involved in the pathogenesis of Duchenne muscular dystrophy (DMD). Ca 2+ influx...

... of Biologists Limited 2005 2005 Duchenne muscular dystrophy Cytoskeleton Motility Syntrophin-associated proteins Utrophin upregulation Dystrophin is a member of the protein family encoded by the Duchenne muscular dystrophy (DMD) gene, which is expressed in muscular and non-muscular tissues...

... this integrin in cases where expression of dystrophin or laminin are compromised. Immunofluorescence demonstrates an increase in α7β1 in patients with Duchenne muscular dystrophy and in mdx mice that lack dystrophin. Analysis of RNA from mdx mice and from patients with Duchenne and Becker muscular dystrophies...

...J. A. Witkowski; V. Dubowitz ABSTRACT Duchenne muscular dystrophy (DMD) is a severe degenerative disorder of skeletal muscle. It has been suggested that an abnormality of the plasma membrane may be responsible for the pathogenesis of DMD, and a number of cell surface changes have been described...