... to the suggested stabilizing role of dystrophin in the context of the membrane-cytoskeletal complex. * Author for correspondence 07 04 1994 11 10 1994 © 1995 by Company of Biologists 1995 dystrophin Duchenne dystrophy MDX mouse myotube muscle culture osmotic shock cytochalasin...

... Duchenne dystrophy adhesion fibroblasts Duchenne muscular dystrophy (DMD) is an X-chromosome-linked wasting disease of human skeletal muscle (Dubowitz & Brooke, 1973), leading to death of affected individuals in their late teens or early twenties (Gardner-Medwin, 1980). Studies from many...

... also suppresses the spreading of human skin fibroblasts when these cells are seeded onto uncoated substrata in serum-free media (Pizzey et al . 1983). In this respect also, DMD fibroblasts are more sensitive than normal cells (Pizzey et al . 1984). cell spreading Duchenne dystrophy monensin...