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Keywords: Dicer1
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Journal Articles
J Cell Sci (2021) 134 (9): jcs253914.
Published: 17 May 2021
... this miRNA. We found that EV-associated miR-122 is primarily single-stranded and, to become functional, is loaded onto the recipient cell argonaute proteins without requiring host Dicer1. Following endocytosis, EV-associated miR-122 is loaded onto the host cell argonaute proteins on the endosomal membrane...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (12): 2314–2327.
Published: 15 June 2015
... spermatocytes possess Dgcr8 and Dicer deletions prior to meiotic initiation. In the current study, we created germline-specific conditional deletions of two proteins needed for small RNA biogenesis, DGCR8 and DICER (also known as DICER1). DGCR8, a component of the endonuclease microprocessor...
Includes: Supplementary data