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Keywords: Development
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Journal Articles
Journal Articles
J Cell Sci (2022) 135 (2): jcs259132.
Published: 24 January 2022
... biosynthetic process and cell morphogenesis involved in gastrulation ( Fig. S4B ). Based on the enrichment of terms involved in development, we wondered whether CHAT regulates developmental genes that first initiate expression during late embryogenesis. To examine this, we compared CHAT-regulated genes...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (22): jcs258834.
Published: 15 November 2021
... of embryonic lethality, phenotypes that are not dependent on stress exposure and that are not shared with gtbp-1 mutants. Our data indicate that, in contrast to human cells, PQN-59 and GTBP-1 are not required for stress granule formation but that PQN-59 is important for C. elegans development. Fig. 7...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (13): jcs258382.
Published: 12 July 2021
... ). Notch signaling functions as a binary switch for the determination of glandular and luminal fates of endodermal epithelium during chicken stomach development . Development 132 , 2783 - 2793 . 10.1242/dev.01853 McClay , D. R. ( 2011 ). Evolutionary crossroads in developmental biology...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (1): jcs246900.
Published: 13 January 2021
... were imaged at regular times during in vitro developmental progression. Pictures were taken daily at the same time five times a day for all embryo sets at ∼08.30 h, ∼10.30 h, ∼01.00 h-02.00 h, ∼16.00 h-17.00 h and ∼20.00 h-21.00 h to compare developmental progression differences between each set...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (17): jcs228015.
Published: 11 September 2020
... , A. A. , Sharova , T. Y. , Scarpa , J. A. , Joffe , B. , Solovei , I. , et al. ( 2014 ). p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells . Development   141 , 101 - 111 . 10.1242/dev...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (23): jcs235127.
Published: 2 December 2019
... and Berx, 2013 ; de Herreros et al., 2010 ; Lamouille et al., 2014 ; Shih and Yang, 2011 ). Snai2 loss causes developmental defects and disturbs homeostasis across multiple tissue systems, whereas increased levels of Snai2 or its dysregulation endorse malignant characteristics during cancer development...
Journal Articles
J Cell Sci (2017) 130 (24): 4097–4107.
Published: 15 December 2017
... polymerase II during the early development of sea urchin. (A) Immunofluorescence staining of active RNA polymerase II. Embryos at each developmental stage were stained with antibody against the RNA polymerase II C-terminal repeat domain YSPTSPS (phosphorylated at Ser5). Green signals indicate active RNA...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (16): 2663–2671.
Published: 15 August 2017
... of germ cells was probably the first task of the p53 protein family, with p63 being its most-ancient member. However, isoform-specific mouse knockout studies have revealed that additional developmental tasks were acquired during evolution. One important aspect of these more-resent functions...
Journal Articles
J Cell Sci (2017) 130 (14): 2394–2404.
Published: 15 July 2017
...-starvation response in which cells begin expressing early developmental genes in anticipation of a high density of cells outgrowing the food supply, thus allowing cells to prepare for the starvation-induced GDT ( Clarke et al., 1988 ; Clarke and Gomer, 1995 ; Maeda, 2005 ). Three pre-starvation factors...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (13): 2134–2146.
Published: 1 July 2017
... embryonic development and continues in the postnatal period ( Lallemend and Ernfors, 2012 ). While developmental changes of ion channel and growth factor receptor expression have been investigated previously ( Benn et al., 2001 ; Hjerling-Leffler et al., 2007 ; Lechner et al., 2009 ; Marmigère...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (11): 1952–1964.
Published: 1 June 2017
... p38-MAPK Development The human prostate gland contains an epithelial bilayer of basal and luminal cells. Within these layers resides a combination of uni- and bi-potent progenitors important for normal gland homeostasis ( Kwon et al., 2016 ; Ousset et al., 2012 ; Uzgare et al., 2004...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (9): 1532–1544.
Published: 1 May 2017
... utilize unique promoters and enhancers to drive expression with distinct developmental timing and tissue specificity. However, in both normal and disease states, multiple Wnt genes are often expressed in combination ( Akiri et al., 2009 ; Bafico et al., 2004 ; Benhaj et al., 2006 ; Suzuki et al., 2004...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (10): 1951–1961.
Published: 15 May 2016
... is a central part of many cell and developmental processes. A surprisingly large number of different molecular mechanisms exist to move nuclei to specific, intracellular locations. LINC complex Development Nuclear envelope Nuclear migration Nuclear migration and positioning are essential...
Journal Articles
J Cell Sci (2016) 129 (6): 1115–1127.
Published: 15 March 2016
... complex Nuclear structure Xenopus Cancer Melanoma Development Nuclear size Nuclear scaling Cell size varies when comparing different species and tissue types, and dramatic changes in cell size accompany early development and cell differentiation within the same organism. A fundamental...
Journal Articles
J Cell Sci (2016) 129 (5): 898–911.
Published: 1 March 2016
... of AChRs. We generated phosphorylation (phospho)-specific antibodies to these sites and used them to demonstrate developmental and nerve-dependent regulation of phosphorylation of α-dystrobrevin-1 at the NMJ. We next identified sets of proteins that interact with α-dystrobrevin-1 in phospho-dependent...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (21): 3990–3996.
Published: 1 November 2015
... and allorecognition during development. TgrB1 and TgrC1 form a heterophilic adhesion complex during cell contact and mediate intercellular communication. The underlying signaling pathways, however, have not been characterized. Here, we report on a mutation that suppresses the tgrB–tgrC1 -defective developmental...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (7): 1408–1421.
Published: 1 April 2015
.../dbio.1997.8566 Freeman   S. D. , Moore   W. M. , Guiral   E. C. , Holme   A. D. , Turnbull   J. E. , Pownall   M. E. ( 2008 ). Extracellular regulation of developmental cell signaling by XtSulf1.   Dev. Biol.   320 , 436 – 445 . 10.1016/j.ydbio.2008.05.554 Gilchrist...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (6): 1139–1149.
Published: 15 March 2015
...@vasci.umass.edu ) Competing interests The authors declare no competing or financial interests. 10 09 2014 16 01 2015 © 2015. Published by The Company of Biologists Ltd 2015 ADAM Development Neural crest Wnt Xenopus laevis The cranial neural crest (CNC) is a stem cell...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (18): 3970–3982.
Published: 15 September 2014
... and wnt8b share a common activity but are involved in distinct developmental pathways.   Development   121 , 1787 – 1799 . Kikuchi   A. , Yamamoto   H. , Sato   A. ( 2009 ). Selective activation mechanisms of Wnt signaling pathways.   Trends Cell Biol.   19 , 119 – 129 . 10.1016/j.tcb...
Includes: Supplementary data