1-20 of 29
Keywords: Desmosomes
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci (2021) 134 (21): jcs258418.
Published: 5 November 2021
..., ablation of ET-20 lncRNA effectively blocks Tnc expression and with it EMT. Mechanistically, ET-20 interacts with desmosomal proteins, thereby impairing epithelial desmosomes and promoting EMT. A short transcript variant of ET-20 is shown to be upregulated in invasive human breast cancer cell lines, where...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (8): jcs238295.
Published: 16 April 2020
...Lisa Müller; Katrin Rietscher; René Keil; Marvin Neuholz; Mechthild Hatzfeld ABSTRACT Desmosome remodeling is crucial for epidermal regeneration, differentiation and wound healing. It is mediated by adapting the composition, and by post-translational modifications, of constituent proteins. We have...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (10): jcs212191.
Published: 22 May 2018
...Katrin Rietscher; René Keil; Annemarie Jordan; Mechthild Hatzfeld ABSTRACT Desmosomes are essential for strong intercellular adhesion and are abundant in tissues exposed to mechanical strain. At the same time, desmosomes need to be dynamic to allow for remodeling of epithelia during differentiation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (20): 3437–3445.
Published: 15 October 2017
... mutations promulgate a mechanical role for this important cytoskeletal component. In stratified epithelia, keratin filaments form prominent radial spokes that are focused onto cell-cell contact sites, i.e. the desmosomes. In this Hypothesis, we draw attention to a subset of keratin filaments...
Journal Articles
J Cell Sci (2014) 127 (11): 2507–2517.
Published: 1 June 2014
...Andrew R. Harris; Alicia Daeden; Guillaume T. Charras ABSTRACT Adherens junctions and desmosomes integrate the cytoskeletons of adjacent cells into a mechanical syncitium. In doing so, intercellular junctions endow tissues with the strength needed to withstand the mechanical stresses encountered...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (13): 3202–3209.
Published: 1 July 2012
... cadherin- and integrin-based adhesion structures and hence epidermal function. In this study, we show that a member of this family, Rnd3, regulates desmosomal cell–cell adhesion in that loss of Rnd3 expression leads to an increase in desmosomes at sites of cell–cell adhesion and altered colony morphology...
Journal Articles
Journal Articles
J Cell Sci (2011) 124 (5): 745–754.
Published: 1 March 2011
... finding in our study of teeth in Perp -null mice was the separation and ectopic displacement of the ameloblasts from the SI at the secretory and transitional stages of amelogenesis. This observation is consistent with the reduced number and size of desmosomes at the ameloblast–SI interface in the teeth...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (21): 3561–3569.
Published: 1 November 2008
...Lisa M. Sevilla; Rachida Nachat; Karen R. Groot; Fiona M. Watt Kazrin is an evolutionarily conserved protein that is upregulated during keratinocyte terminal differentiation. Kazrin localizes to desmosomes and binds the epidermal cornified envelope protein periplakin. Kazrin overexpression in human...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (17): 2844–2849.
Published: 1 September 2008
...Jiangli Chen; Zhining Den; Peter J. Koch Desmocollin 3 (DSC3) belongs to a subfamily of cadherins and is a major component of desmosomes in keratinocytes of stratified epithelia, such as the epidermis. Based on its amino acid sequence homology to classical cadherins, such as E-cadherin, it has been...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (1993) 104 (3): 741–750.
Published: 1 March 1993
...Joachim Arnemann; Kate H. Sullivan; Anthony I. Magee; Ian A. King; Roger S. Buxton ABSTRACT Desmosomal junctions are abundant in epidermis and contain two classes of transmembrane glycoprotein, the desmocollins and the desmogleins, which are members of the cadherin superfamily of Ca 2+ -dependent...
Journal Articles
Journal Articles
J Cell Sci (1992) 103 (1): 69–80.
Published: 1 September 1992
...Katrina T. Trevor; Lara S. Steben ABSTRACT In diverse epithelia, cytoskeletal keratin intermediate filaments (IFs) associate with the cytoplasmic face of intercelluar junctional desmosomes. The processes underlying desmosome formation and keratin IF interactions remain unclear. We have examined F9...
Journal Articles
J Cell Sci (1990) 97 (4): 689–704.
Published: 1 December 1990
...D. L. Mattey; G. Burdge; D. R. Garrod ABSTRACT The development or maturation of intercellular adhesions following their initiation has received very little attention even though this is an area of significance for a variety of in vivo processes. Using Ca 2+ -induced desmosome formation in MDCK...
Journal Articles
Journal Articles