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Keywords: Desmoplakin
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Journal Articles
J Cell Sci (2012) 125 (12): 2853–2861.
Published: 15 June 2012
... function due to inherited mutations in the constitutive desmosomal gene desmoplakin ( DSP ) causes skin or heart disorders and in some instances both. Different mutations have different disease-causing molecular mechanisms as evidenced by the varying phenotypes resulting from mutations affecting different...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (23): 4974–4985.
Published: 1 December 2006
... muscle cells. The desmosomal component desmoplakin plays a key role in tethering various intermediate filament networks through its C-terminal plakin repeat domain. To gain better insight into the cytoskeletal organization of cardiomyocytes, we investigated the association of desmoplakin with desmin...
Journal Articles
J Cell Sci (2004) 117 (15): 3129–3140.
Published: 1 July 2004
...Xuan Zhou; August Stuart; Luis E. Dettin; Gisela Rodriguez; Bonnie Hoel; G. Ian Gallicano Desmoplakin (DP) is a key component of cellular adhesion junctions known as desmosomes; however, recent investigations have revealed a novel location for DP in junctions separate from desmosomes termed...
Journal Articles
Journal Articles
J Cell Sci (2003) 116 (5): 875–885.
Published: 1 March 2003
... of desmosomes in cardiac myocytes in the absence of Cx43, we double stained for Cx43 and desmoplakin, a necessary component of desmosomes ( Fig. 4 ). As seen with adherens-junction-associated cadherin staining,gap junctions and desmosomes were often juxtaposed at the intercalated disc( Fig. 4E ). However...
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (1997) 110 (1): 23–33.
Published: 1 January 1997
... is disruption of desmoplakin organization at the cell surface, indicating dissociation of desmosomes. This effect is followed by a dramatic reorganization of both the intermediate filament (keratins 8 and 18) and microfilament networks, resulting in a merged structure in which the intermediate filaments...
Journal Articles
Journal Articles
J Cell Sci (1990) 97 (2): 247–257.
Published: 1 October 1990
...Bright D. Angst; Laura A. Nilles; Kathleen J. Green ABSTRACT Desmosomes are major intercellular junctions found in association with intermediate filaments in epithelial, cardiac and arachnoidal tissue. Desmoplakins I and II (DPI and II) are highly related proteins localized in the innermost part...
Journal Articles
J Cell Sci (1986) 86 (1): 233–248.
Published: 1 December 1986
... and antibodies to desmoplakin and vinculin were used as markers for the presence of desmosomes and fasciae adherentes, respectively. Tiny punctate desmosomes were observed between muscle cells after 24 h and apparently increased in number and/or size between 24 and 48 h in culture. Fasciae adherentes were...