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Keywords: DNA synthesis
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Journal Articles
J Cell Sci (2006) 119 (23): 4944–4951.
Published: 1 December 2006
...Kimihiko Sugaya; Etsuko Hongo; Yoshie Ishihara; Hideo Tsuji Temperature-sensitive CHO-K1 mutant cell line tsTM18 exhibits chromosomal instability and cell-cycle arrest at S and G2 phases with decreased DNA synthesis at the nonpermissive temperature, 39°C. We previously identified an amino acid...
Journal Articles
J Cell Sci (2006) 119 (14): 2921–2934.
Published: 15 July 2006
... signalling including kinase activation, Myc gene induction and DNA synthesis. The impact of caveolae on SFK function was underscored by the capacity of Myc to overcome mitogenic inhibition as a result of caveolae disruption. Using biochemical fractionation we show that caveolae-enriched subcellular membranes...
Journal Articles
J Cell Sci (2006) 119 (6): 1026–1033.
Published: 15 March 2006
..., the number of PML nuclear bodies has increased by a factor of twofold. Association of the fission products with chromatin implies that the PML nuclear bodies respond to changes in chromatin organisation or topology, and thus could play a role in monitoring genome integrity during DNA synthesis...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2004) 117 (25): 6043–6051.
Published: 1 December 2004
...Xiujie Zhao; Susan McKillop-Smith; Berndt Müller Histone proteins are essential for chromatin formation, and histone gene expression is coupled to DNA synthesis. In metazoans, the histone RNA binding protein HBP/SLBP is involved in post-transcriptional control of histone gene expression. In vitro...
Journal Articles
J Cell Sci (2004) 117 (3): 465–476.
Published: 22 January 2004
... later in S phase. Nuclear accumulation of YY1 near the G1/S boundary coincided with both an increase in YY1 DNA-binding activity and the coordinate up-regulation of the replication-dependent histone genes. The DNA synthesis inhibitor aphidicolin caused a nearly complete loss of nuclear YY1, whereas...
Journal Articles
J Cell Sci (2004) 117 (3): 507–514.
Published: 22 January 2004
... that serine-262 (S262) on Cx43 becomes phosphorylated in response to growth factor or PKC stimulation of cardiomyocytes. To examine the effect of Cx43, S262 phosphorylation and cell-cell contact (and/or coupling) on DNA synthesis, we overexpressed wild-type (wt) or mutant Cx43, carrying a S262-to-alanine...
Journal Articles
J Cell Sci (2002) 115 (22): 4353–4360.
Published: 15 November 2002
... to thrombospondin-1. Cellular signals were identified by western blotting following cell stimulation, while cellular responses were assessed by measuring DNA synthesis and chemotaxis. These data demonstrate that thrombospondin-1-induced cell chemotaxis can be inhibited by a peptide containing the Arg-Gly-Asp motif...
Journal Articles
J Cell Sci (2002) 115 (8): 1623–1634.
Published: 15 April 2002
... in myocytes normally withdrawn from the cell cycle. § Author for correspondence (e-mail: radice@mail.med.upenn.edu ) 21 1 2002 © The Company of Biologists Limited 2002 2002 Transgenic Cell adhesion Cardiac hypertrophy Cyclin D1 DNA synthesis The structural integrity...