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Keywords: DNA methylation
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J Cell Sci (2013) 126 (10): 2256–2266.
Published: 15 May 2013
... DNA methylation and histone modifications were significantly altered in the stem-like and non-stem phenotypes. In particular, in the stem-like phenotype, the miR-200b-200a-429 cluster was silenced primarily through polycomb group-mediated histone modifications whereas the miR-200c-141 cluster...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (22): 5524–5534.
Published: 15 November 2012
...Joe Burrage; Ausma Termanis; Andreas Geissner; Kevin Myant; Katrina Gordon; Irina Stancheva Summary LSH, a protein related to the SNF2 family of chromatin-remodelling ATPases, is essential for the correct establishment of DNA methylation levels and patterns in plants and mammalian cells. However...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (9): 2276–2287.
Published: 1 May 2012
... such as migration, extracellular matrix production and assembly in 3D self-assembled tissues. To determine potential regulatory regions predictive of expression of PDGFRβ following differentiation from ESCs and iPSCs, we analyzed the DNA methylation status of a region of the PDGFRB promoter that contains multiple...
Includes: Supplementary data
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J Cell Sci (2008) 121 (6): 906–912.
Published: 15 March 2008
... FERTILIZATION INDEPENDENT SEED genes DNA methylation Polycomb group proteins A subset of genes in mammals and flowering plants is only expressed from one of the two homologous chromosomes, depending on whether they are maternally or paternally inherited. This process is called genomic imprinting...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (1): 101–114.
Published: 1 January 2007
... hybridization, Aurora-B and H3S10 phosphorylated foci were found more frequently at larger pericentromeres than at smaller ones, revealing a preferential phosphorylation of pericentromeres, exhibiting a high density of methyl cytosines. Disruption of DNA methylation inhibited pericentromeric Aurora-B targeting...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (15): 3033–3037.
Published: 1 August 2006
... Limited 2006 2006 DNA methylation Transcriptional repression Epigenetics Methyl CpG binding protein Eukaryotic chromosomes are the repositories of the genetic information necessary to direct the synthesis of cellular components. Information is embedded in them at multiple levels...
Journal Articles
Journal Articles
J Cell Sci (1995) 1995 (Supplement_19): 37–39.
Published: 1 January 1995
...Adrian Bird; Peri Tate; Xinsheng Nan; Javier Campoy; Richard Meehan; Sally Cross; Susan Tweedie; Jillian Charlton; Donald Macleod ABSTRACT We have been studying the evolution and function of DNA methylation in vertebrate animals using three related approaches. The first is to further characterise...
Journal Articles
J Cell Sci (1992) 1992 (Supplement_16): 9–14.
Published: 1 January 1992
.... © The Company of Biologists Limited 1992 1992 DNA methylation transcriptional repression methyl-CpG binding proteins In mammals approximately 70% of all CpGs are methylated at the 5 position of cytosine. It is not clear what the functional role of this modification is, but it has...
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J Cell Sci (1989) 92 (4): 723–732.
Published: 1 April 1989
...Stephen G. Grant; Ronald G. Worton ABSTRACT Treatment with 5-azacytidine, a potent inhibitor of DNA methylation, was used to induce activation of the selectable hprt gene on the inactive X chromosome in a diploid female Chinese hamster cell line. The transformed, stably diploid cell line F3B...