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Keywords: DKK1
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Journal Articles
J Cell Sci (2019) 132 (10): jcs228478.
Published: 16 May 2019
...Liying Liang; Yalin Tu; Jing Lu; Panxia Wang; Zhen Guo; Qianqian Wang; Kaiteng Guo; Rui Lan; Hong Li; Peiqing Liu ABSTRACT The cancer clinical therapy of doxorubicin (Dox) treatment is limited by its life-threatening cardiotoxic effects. Dickkopf-1 (Dkk1), the founding and best-studied member...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (3): 360–368.
Published: 1 February 2010
.... Dickkopf1 (Dkk1) has been shown to inhibit the Wnt— β-catenin pathway, but the mechanism is not yet clear. Here, evidence is presented that Wnt3a-dependent phosphorylation of LRP6 occurs in the lipid raft and that Dkk1 inhibits the formation of a complex between LRP6 and casein kinase 1γ (CK1γ) by removing...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (22): 5305–5314.
Published: 15 November 2005
... recombinant DKK1 protein and mouse recombinant Wnt3a protein were from R&D Systems. Human recombinant RAP protein was expressed in a glutathione S -transferase (GST) expression vector and isolated as described previously ( Bu et al., 1993 ). Monoclonal anti-Myc antibody 9E10 was from Roche. Monoclonal...