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Keywords: Cytochalasin D
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Journal Articles
J Cell Sci (2004) 117 (2): 271–280.
Published: 15 January 2004
... tissue-specific gene-expression. Curr. Opin. Cell Biol. 7 , 736 -747. Sastry, S. K. and Burridge, K. ( 2000 ). Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics. Exp. Cell Res. 261 , 25 -36. Schliwa, M. ( 1982 ). Action of cytochalasin D on cytoskeletal...
Journal Articles
J Cell Sci (2003) 116 (8): 1617–1625.
Published: 15 April 2003
... activity with the rate of cell spreading on a substratum. The rate of spreading is inversely related to the myosin activity. Furthermore, spreading is inhibited by low concentrations of cytochalasin D,as expected for a process that depends on the growth of uncapped actin filaments. Cell indentation...
Journal Articles
J Cell Sci (2001) 114 (5): 1025–1036.
Published: 1 March 2001
.... Therefore, the state of the actin cytoskeleton strongly influences the mechanical properties of cells and tissues. Cytochalasin D and Latrunculin are commonly used reagents that, by different mechanisms, alter the state of actin polymerization or the organization of actin filaments. We have investigated...
Journal Articles
J Cell Sci (1999) 112 (17): 2853–2865.
Published: 1 September 1999
.... In contrast, there was no detectable diminution of myosin-V staining at the centrosome in cells treated with the actin filament-disrupting drug cytochalasin D. Thus, while localization of the myosin-V motor domain to actin-rich regions is consistent with conventional models of actomyosin-based motility...
Journal Articles
J Cell Sci (1999) 112 (1): 81–96.
Published: 1 January 1999
...Karine M. Valentijn; Francine D. Gumkowski; James D. Jamieson ABSTRACT We examined the effects of disruption of the actin cytoskeleton by cytochalasin D (cytoD) on basal and carbamylcholine-stimulated exocytosis and on compensatory membrane retrieval in pancreatic acinar cells. Although...
Journal Articles
J Cell Sci (1995) 108 (2): 727–733.
Published: 1 February 1995
.... Control experiments indicated that this difference is not due to differences in metabolism or ion fluxes. Treatment with cytochalasin D drastically increased the shock sensitivity of myotubes and abolished the difference between dystrophin-less and control cells. These results lend further support...
Journal Articles
Journal Articles
J Cell Sci (1992) 103 (1): 15–22.
Published: 1 September 1992
... during normal infections. Cytochalasin D, known to interfere with nucleocapsid morphogenesis, uncoupled the apparent co-localization of F-actin and the capsid protein and inhibited infectious progeny production. Inhibition was reversible throughout infection (even in the presence of a protein synthesis...
Journal Articles
J Cell Sci (1992) 101 (4): 895–905.
Published: 1 April 1992
... by cytochalasin D, a drug that is unable to prevent trypomastigote entry into HeLa cells. The internalization of the membrane expansion, however, is blocked by the drug. These novel observations indicate that although the driving force for T. cruzi penetration comes from the parasite, the cortical target...
Journal Articles
J Cell Sci (1990) 97 (1): 59–70.
Published: 1 September 1990
... in their retraction. The addition of taxol to cultures resulted in abnormally thick processes that were tightly adherent to the underlying substratum, and did not bead or fragment Cytochalasin D accelerated process formation and fragmentation of megakaryocytes cultured on collagen gels by twofold. On the basis...
Journal Articles
J Cell Sci (1989) 94 (4): 635–646.
Published: 1 December 1989
... with the site of new wall formation and the timing of rearrangement of actin coincided with the initiation of cell wall formation and with the timing of cell wall expansion. Treatment of reverting protoplasts with cytochalasin D (CD) further clarified the close relationship between actin and cell wall...