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1-6 of 6
Keywords: Cysteine protease
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Journal Articles
In collection:
Cell biology and disease
Krishanu Bhowmick, Ankita Tehlan, Sunita, Renu Sudhakar, Inderjeet Kaur, Puran Singh Sijwali, Annangarachari Krishnamachari, Suman Kumar Dhar
Journal:
Journal of Cell Science
J Cell Sci (2020) 133 (1): jcs236489.
Published: 9 January 2020
... expression in the parasite. Here, we show the existence of a novel proteolytic processing for PfGCN5 that is crucial for its activity in vivo . We find that a cysteine protease-like enzyme is required for the processing of PfGCN5 protein. Immunofluorescence and immuno-electron microscopy analysis suggest...
Includes: Supplementary data
Journal Articles
Camila C. Santos, Celso Sant'Anna, Amanda Terres, Narcisa L. Cunha-e-Silva, Julio Scharfstein, Ana Paula C. de A. Lima
Journal:
Journal of Cell Science
J Cell Sci (2005) 118 (5): 901–915.
Published: 1 March 2005
...Camila C. Santos; Celso Sant'Anna; Amanda Terres; Narcisa L. Cunha-e-Silva; Julio Scharfstein; Ana Paula C. de A. Lima Chagasin is a Trypanosoma cruzi protein that was recently characterized as a tight-binding inhibitor of papain-like cysteine proteases (CPs). Considering that parasite virulence...
Journal Articles
Ana C. S. Monteiro, Magnus Abrahamson, Ana P. C. A. Lima, Marcos A. Vannier-Santos, Julio Scharfstein
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (21): 3933–3942.
Published: 1 November 2001
...Ana C. S. Monteiro; Magnus Abrahamson; Ana P. C. A. Lima; Marcos A. Vannier-Santos; Julio Scharfstein Lysosomal cysteine proteases from mammalian cells and plants are regulated by endogenous tight-binding inhibitors from the cystatin superfamily. The presence of cystatin-like inhibitors in lower...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2000) 113 (22): 4035–4041.
Published: 15 November 2000
...Darren R. Brooks; Laurence Tetley; Graham H. Coombs; Jeremy C. Mottram ABSTRACT Removal of the pro-domain of a cysteine protease is essential for activation of the enzyme. We have engineered a cysteine protease (CPB2.8) of the protozoan parasite Leishmania mexicana by site-directed mutagenesis...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (1995) 108 (10): 3219–3231.
Published: 1 October 1995
..., or if amastigotes were pre-treated with the irreversible cysteine protease inhibitor Z-Phe-AlaCHN2 before infection, clearly indicating that amastigotes also degraded the internalized class II molecules. Study of infected macrophage cryosections by immuno-electron microscopy allowed the identification of the class...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (1994) 107 (2): 373–384.
Published: 1 February 1994
... 09 1993 27 10 1993 © 1994 by Company of Biologists 1994 cathepsin cysteine protease breast cancer neoplasia ras Increases in expression, alterations in subcellular distribution and increases in secretion of lysosomal proteases have been reported to parallel malignant...