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Keywords: Copper
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Journal Articles
J Cell Sci (2021) 134 (21): jcs240523.
Published: 4 November 2021
...Svetlana Lutsenko ABSTRACT Copper (Cu) homeostasis is essential for the development and function of many organisms. In humans, Cu misbalance causes serious pathologies and has been observed in a growing number of diseases. This Review focuses on mammalian Cu(I) transporters and highlights recent...
Journal Articles
J Cell Sci (2016) 129 (11): 2190–2201.
Published: 1 June 2016
...: Excess Cu + induces the transport of ATP7B from the TGN to the membrane of the bile canaliculus through basolateral sorting and transcytosis for biliary Cu + excretion without lysosomal involvement. Copper ATP7B Trafficking TGN Bile canaliculus Transcytosis The redox properties of Cu...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (10): 1518–1528.
Published: 15 May 2009
..., with amelioration when copper bound. Amino acid residues 23-50 alone mediated a ROS reduction response. PrP23-50 ROS reduction was not due to copper binding or direct antioxidant activity, but was instead mediated through proteoglycan binding partners localised in or interacting with cholesterol-rich membrane...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (9): 1315–1321.
Published: 1 May 2009
...Carine White; Taiho Kambe; Yan G. Fulcher; Sherri W. Sachdev; Ashley I. Bush; Kevin Fritsche; Jaekwon Lee; Thomas P. Quinn; Michael J. Petris Copper is an essential nutrient for a variety of biochemical processes; however, the redox properties of copper also make it potentially toxic in the free...
Journal Articles
Journal Articles
J Cell Sci (2003) 116 (24): 4871–4881.
Published: 15 December 2003
...@mmc.org ) © The Company of Biologists Limited 2003 2003 Fibroblast growth factor 1 FGF1 Interleukin 1α IL-1α Release Non-classical Copper Synaptotagmin 1 S100A13 Many biological processes involve polypeptide translocation across phospholipid membranes. Among them are export...
Journal Articles
Journal Articles
J Cell Sci (1987) 88 (3): 283–293.
Published: 1 October 1987
...E. Piccinni; P. Irato; O. Coppellotti; L. Guidolin ABSTRACT The addition of copper (10 μ gml −1 ) or cadmium (5 μ gml −1 ) to the medium is well tolerated by Tetrahymena pyriformis GL. Both metals are accumulated by cells, cadmium to a greater extent than copper. The growth rate is not affected...