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Keywords: Connexin43
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Journal Articles
Journal Articles
J Cell Sci (2014) 127 (15): 3269–3279.
Published: 1 August 2014
... downstream effects on cellular processes. Here, we identify an interaction between the T-cell protein tyrosine phosphatase (TC-PTP, officially known as PTPN2) and the carboxyl terminus of connexin43 (Cx43, officially known as GJA1). Two cell lines, normal rat kidney (NRK) cells endogenously expressing Cx43...
Journal Articles
J Cell Sci (2014) 127 (2): 455–464.
Published: 15 January 2014
...Clarence A. Dunn; Paul D. Lampe ABSTRACT The proteins that form vertebrate gap junctions, the connexins, are highly regulated and have short (<2 hour) half-lives. Phosphorylation of connexin43 (Cx43) affects gap junction assembly, channel gating and turnover. After finding dramatic effects...
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J Cell Sci (2011) 124 (15): 2611–2621.
Published: 1 August 2011
...Steven Machtaler; May Dang-Lawson; Kate Choi; Caren Jang; Christian C. Naus; Linda Matsuuchi The gap junction protein connexin43 (Cx43) is widely expressed in mammalian cells and forms intercellular channels for the transfer of small molecules between adjacent cells, as well as hemichannels...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (24): 4029–4036.
Published: 15 December 2008
... and induced a G2-M arrest in ANSCs. Using Fluo-3 Ca 2+ imaging, we show that AQP4 knockout alters the spontaneous Ca 2+ oscillations by frequency enhancement and amplitude suppression, and suppresses KCl-induced Ca 2+ influx. AQP4 knockout downregulated the expression of connexin43 and the L-type voltage...
Journal Articles
Journal Articles
J Cell Sci (2006) 119 (21): 4510–4519.
Published: 1 November 2006
...Mónica R. Calera; Heather L. Topley; Yongbo Liao; Brian R. Duling; David L. Paul; Daniel A. Goodenough Connexin43 is a major component of the gap junctions between pigmented and non-pigmented cells of the double-layered epithelium in the ciliary body of the eye. We directly tested the hypothesis...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2006) 119 (16): 3435–3442.
Published: 15 August 2006
...Paul D. Lampe; Cynthia D. Cooper; Timothy J. King; Janis M. Burt The functional consequences of Connexin43 (Cx43) phosphorylation remain largely unexplored. Using an antibody that specifically recognizes Cx43 phosphorylated at serine residues 325, 328 and/or 330 (pS325/328/330-Cx43), we show...
Journal Articles
Journal Articles
J Cell Sci (2005) 118 (1): 113–122.
Published: 1 January 2005
...Joanne E. I. Gittens; Kevin J. Barr; Barbara C. Vanderhyden; Gerald M. Kidder Intercellular communication is required for ovarian folliculogenesis. This is apparent in mice lacking connexin43 (Cx43, a gap junction protein strongly expressed in granulosa cells), or growth/differentiation factor-9...
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J Cell Sci (2003) 116 (5): 875–885.
Published: 1 March 2003
... whether loss of cardiac gap junctions, such as described in cardiac disease states, may influence the expression patterns of other intercalated disc-associated proteins. We investigated whether the major cardiac gap junction protein connexin43 (Cx43) may be responsible for regulating adherens junctions...
Journal Articles