...Harry Scott; Li Dong; Andrew Stevenson; Alasdair I. MacDonald; Sharmila Srinivasan; Paola Massimi; Lawrence Banks; Patricia E. Martin; Scott R. Johnstone; Sheila V. Graham ABSTRACT Gap junction channels, composed of connexins, allow direct cell-to-cell communication. Connexin 43 (Cx43; also known...

... called connexosomes or annular gap junctions. Here, we systematically investigated the fate of connexosomes in intact ovarian follicles. High-pressure frozen, serial-sectioned tissue was immunogold labeled for connexin 43 (Cx43, also known as GJA1). Within a volume corresponding to ∼35 cells, every...

...Karyn Jourdeuil; Lisa A. Taneyhill ABSTRACT Gap junctions are intercellular channels between cells that facilitate cell–cell communication. Connexin 43 (Cx43; also known as GJA1), the predominant gap junction protein in vertebrates, is expressed in premigratory cranial neural crest cells...

...Kristin J. Lastwika; Clarence A. Dunn; Joell L. Solan; Paul D. Lampe ABSTRACT The gap junction protein connexin 43 (Cx43) is a key player in wound healing, and inhibitors of Cx43, which speed epidermal wound healing, are currently in clinical trials. Here, we provide direct in vivo evidence...

... 2018. Published by The Company of Biologists Ltd 2018 http://www.biologists.com/user-licence-1-1/ Summary: Connexin 43 in gap junctions becomes K63-polyubiquitylated on lysines 264 and 303, which is required for gap junction endocytosis. Connexin 43 Endocytosis Gap junctions...

... studies have shown that connexin 43 (Cx43, also known as GJA1), a transmembrane protein initially described as a gap junction protein, participates in all these forms of communication; this emphasizes the concept of adopting strategies to maximize the potential of available resources by reutilizing...

...Masaki Ishikawa; Geneva L. Williams; Tomoko Ikeuchi; Kiyoshi Sakai; Satoshi Fukumoto; Yoshihiko Yamada ABSTRACT Pannexin 3 (Panx3) and connexin 43 (Cx43; also known as GJA1) are two major gap junction proteins expressed in osteoblasts. Here, we studied their functional relationships in skeletal...

... specific AKAPs are depleted by siRNA-mediated knockdown, point to ezrin as a scaffold required for hCG-, cAMP- and PKA-mediated regulation of the fusion process. By a variety of immunoprecipitation and immunolocalization experiments, we show that ezrin directs PKA to a molecular complex of connexin 43...

... contributed equally to this work 26 1 2004 © The Company of Biologists Limited 2004 2004 Gap junctions Cx37 Cx43 Ovarian follicle Oocyte Cumulus granulosa cell Connexin 43 Gap junctions are clusters of intercellular channels that aggregate at sites of close cell-cell...

...Takahiko Ogawa; Tomonori Hayashi; Seishi Kyoizumi; Yoichiro Kusunoki; Kei Nakachi; Donald G. MacPhee; James E. Trosko; Katsuko Kataoka; Noriaki Yorioka Phosphorylation of connexin 43 (Cx43) molecules (e.g. by extracellular signal-regulated kinase) leads to reductions in gap-junctional intercellular...