... ) ( Fig. S1A ). We crossed Nfatc1-Cre/Dicer1 loxp/+ male mice with Dicer1 loxp/loxp female mice ( Cobb et al., 2005 ) to obtain conditional knockout (cKO; Nfatc1-Cre/Dicer1 loxp/loxp ) and control ( Dicer1 loxp/+ or Dicer1 loxp/loxp ) animals. Our quantitative real-time RT-PCR (qRT-PCR...

... of Biologists Ltd 2021 Highlighted Article: We established conditional knockout cell lines for Rab1 and Rab5, and found that loss of Rab1 induced perinuclear accumulation of early endosomes and that Rab5 was dispensable for lysosome biogenesis. Auxin-inducible degron (AID) Cell survival Cell...

... 2015. Published by The Company of Biologists Ltd 2015 Highlighted Article:   In vivo evidence showing that PP6 in oocytes suppresses Aurora A activity in MII and is crucial for MII exit, euploid egg production and female fertility. Conditional knockout PP6 Aurora A Oocyte MII exit...

... and that it functions by accelerating keratinocyte migration, rather than proliferation. ‡ Author for correspondence (e-mail: shirakat@m.ehime-u.ac.jp ) * These authors contributed equally to this work 14 2 2005 © The Company of Biologists Limited 2005 2005 Conditional knockout HB-EGF...