...Laura Breimann; Ana Karina Morao; Jun Kim; David Sebastian Jimenez; Nina Maryn; Krishna Bikkasani; Michael J. Carrozza; Sarah E. Albritton; Maxwell Kramer; Lena Annika Street; Kustrim Cerimi; Vic-Fabienne Schumann; Ella Bahry; Stephan Preibisch; Andrew Woehler; Sevinç Ercan ABSTRACT Condensin...

...Avi Matityahu; Itay Onn ABSTRACT The three-dimensional structure of chromatin is determined by the action of protein complexes of the structural maintenance of chromosome (SMC) family. Eukaryotic cells contain three SMC complexes, cohesin, condensin, and a complex of Smc5 and Smc6. Initially...

...Emily Deutschman; Jacqueline R. Ward; Avinash Kumar; Greeshma Ray; Nicole Welch; Madeleine E. Lemieux; Srinivisan Dasarathy; Michelle S. Longworth ABSTRACT The maintenance of mitochondrial respiratory function and homeostasis is essential to human health. Here, we identify condensin II subunits...

...Robert V. Skibbens ABSTRACT Condensins and cohesins are highly conserved complexes that tether together DNA loci within a single DNA molecule to produce DNA loops. Condensin and cohesin structures, however, are different, and the DNA loops produced by each underlie distinct cell processes...

...Masatoshi Takagi; Takao Ono; Toyoaki Natsume; Chiyomi Sakamoto; Mitsuyoshi Nakao; Noriko Saitoh; Masato T. Kanemaki; Tatsuya Hirano; Naoko Imamoto ABSTRACT Although condensins play essential roles in mitotic chromosome assembly, Ki-67 (also known as MKI67), a protein localizing to the periphery...

...Kumiko Samejima; Daniel G. Booth; Hiromi Ogawa; James R. Paulson; Linfeng Xie; Cara A. Watson; Melpomeni Platani; Masato T. Kanemaki; William C. Earnshaw ABSTRACT The requirement for condensin in chromosome formation in somatic cells remains unclear, as imperfectly condensed chromosomes do form...

... of modern cell biology is to understand how such macromolecular complexes are assembled efficiently and find their destinations faithfully. In this Opinion article, we will focus on HEAT repeats, flexible arrays of amphiphilic helices found in many eukaryotic proteins, such as karyopherins and condensins...

... through the function of condensin. However, the dynamics of these condensin-mediated genomic associations remains unknown. We have examined the 3D motions of genomic loci including the centromere, telomere, rDNA repeat locus, and the loci carrying Pol-III-transcribed genes or long-terminal repeat (LTR...

...Lydia C. Green; Paul Kalitsis; Tsz M. Chang; Miri Cipetic; Ji Hun Kim; Owen Marshall; Lynne Turnbull; Cynthia B. Whitchurch; Paola Vagnarelli; Kumiko Samejima; William C. Earnshaw; K. H. Andy Choo; Damien F. Hudson In vertebrates, two condensin complexes exist, condensin I and condensin II, which...

...Karishma S. Collette; Emily L. Petty; Netta Golenberg; Joshua N. Bembenek; Gyorgyi Csankovszki Condensin complexes are essential for mitotic and meiotic chromosome segregation. Caenorhabditis elegans , like other metazoans, has two distinct mitotic and meiotic condensin complexes (I and II), which...

...Norihiko Nakazawa; Rajesh Mehrotra; Masahiro Ebe; Mitsuhiro Yanagida Condensin is a conserved protein complex that functions in chromosome condensation and segregation. It has not been previously unequivocally determined whether condensin is required throughout mitosis. Here, we examined whether...

...Jesse J. Lipp; Toru Hirota; Ina Poser; Jan-Michael Peters The assembly of mitotic chromosomes is controlled by condensin complexes. In vertebrates, condensin I binds to chromatin in prometaphase, confers rigidity to chromosomes and enables the release of cohesin complexes from chromosome arms...

... Limited 2003 2003 Mitosis Topoisomerase Chromosome segregation Chromosomal passengers Condensin Heterochromatin Type II DNA topoisomerases (Topo II) are essential enzymes that modulate the topology of DNA. Topo II function is necessary for virtually all processes involving double...

...Paula A. Coelho; Joana Queiroz-Machado; Claudio E. Sunkel Assembly of compact mitotic chromosomes and resolution of sister chromatids are two essential processes for the correct segregation of the genome during mitosis. Condensin, a five-subunit protein complex, is thought to be required...

...Rustem Uzbekov; Elmira Timirbulatova; Erwan Watrin; Fabien Cubizolles; David Ogereau; Pavel Gulak; Vincent Legagneux; Vladimir Ju. Polyakov; Katherine Le Guellec; Igor Kireev Cell cycle dynamics and localization of condensins — multiprotein complexes involved in late stages of mitotic chromosome...

...Jacqueline Bomar; Pedro Moreira; John J. Balise; Philippe Collas A-kinase anchoring protein AKAP95 is implicated in somatic mitotic chromosome condensation by recruiting the condensin complex. Here, we report a differential regulation of condensation of maternal and paternal chromosomes mediated...