... by Company of Biologists 2000 Smooth muscle cell Cell migration Collagen degradation PDGF-BB αvβ3 integrin Cell migration is an essential feature of normal development and wound healing, and in pathological conditions such as following cardiovascular damage and tumour invasion...

... © 1994 by Company of Biologists 1994 collagenase collagen degradation EGF IL-1 immunolocalization MMP-1 tissue culture The synthesis and secretion of the matrix metalloproteinase collagenase (MMP-1), an enzyme that plays an important role in the extracellular degradation...

... in cell-mediated collagen degradation. Rabbit chondrocytes were prepared from articular cartilage as described (Trechsel et al . 1982). Rabbit brain capillary endothelial cells were prepared from cerebral microvessels (Banda et al . 1982) and were kindly provided by Dr Michael J. Banda, Laboratory...