...Satoru Higashi; Tomohiko Makiyama; Hiroshi Sakane; Satoru Nogami; Hiromichi Shirataki ABSTRACT In clathrin-independent endocytosis, Hook1, a microtubule- and cargo-tethering protein, participates in sorting of cargo proteins such as CD98 (encoded by SLC3A2 ) and CD147 (encoded by BSG...

... use transformed cells, but the majority of cells in an adult organism have exited the cell cycle. Here, we review endocytosis in dividing, quiescent and terminally differentiated cells. Endocytosis Clathrin-mediated endocytosis Clathrin-independent endocytosis Cell cycle Mitosis Quiescence...

...Debra L. Johnson; Jessica Wayt; Jean M. Wilson; Julie G. Donaldson ABSTRACT Endosomal trafficking can influence the composition of the plasma membrane and the ability of cells to polarize their membranes. Here, we examined whether trafficking through clathrin-independent endocytosis (CIE) affects...

... maturation of plasma membrane internalised by this mechanism. Clathrin-independent endocytosis GRAF1 Cdc42 Cell surface Actin Cell surface dynamics are fundamental to a variety of basic biological processes, such as migration, polarisation and division, as well as protein and lipid...

... and very early uptake structures that are induced by the bacterial Shiga toxin, which enters cells by clathrin-independent endocytosis. We show that toxin trafficking into cells and cell intoxication rely on these SNARE proteins. Of note, the cellular uptake of VAMP3 is increased in the presence of Shiga...

... ). At first glance these findings appear to be in contrast with the expected role of cytosolic PLA 2 enzymes to support membrane tubulation ( Bechler et al., 2011 ; Bechler et al., 2010 ; San Pietro et al., 2009 ; Yang et al., 2011 ). However, the function of cPLA 2 α in clathrin-independent endocytosis...

...-mail: rkelly@research.ucsf.edu ) 25 11 2002 © The Company of Biologists Limited 2003 2003 Synaptotagmin VII Clathrin-dependent endocytosis Clathrin-independent endocytosis Sorting signals Regulated secretion of proteins and lipids requires a precise balance between fusion...