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Keywords: Ciliogenesis
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Journal Articles
Journal Articles
J Cell Sci jcs.261692.
Published: 4 April 2024
...Manu Ahmed; Richard Wheeler; Jiří Týč; Shahaan Shafiq; Jack Sunter; Sue Vaughan Transition fibres and distal appendages surround the distal end of mature basal bodies and are essential for ciliogenesis, but only a few proteins have been identified and functionally characterised. Here, through...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2023) 136 (23): jcs261148.
Published: 14 December 2023
... , C. L. , Josifova , D. J. et al. ( 2011 ). A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition . Nat. Genet. 43 , 776 - 784 . 10.1038/ng.891 Ghossoub , R. , Hu , Q. , Failler , M. , Rouyez , M. C. , Spitzbarth , B...
Journal Articles
J Cell Sci (2023) 136 (3): jcs260560.
Published: 2 February 2023
... in the initial process of ciliogenesis, and subdistal appendages are involved in microtubule anchoring, mitotic spindle regulation and maintenance of ciliary signaling. Mutations in genes encoding components of both appendage types are implicated in ciliopathies and developmental defects. In this Review, we...
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2022) 135 (10): jcs259396.
Published: 17 May 2022
...) heterodimer or a variety of other SNX proteins. Despite involvement in yeast and mammalian cell trafficking, the role of retromer in development is poorly understood, and its impact on primary ciliogenesis remains unknown. Using CRISPR/Cas9 editing , we demonstrate that vps-26 -knockout worms have reduced...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2021) 134 (14): jcs258397.
Published: 20 July 2021
.... © 2021. Published by The Company of Biologists Ltd 2021 Summary: The role of centrosomal γ-tubulin ring complex (γTuRC) is generally believed to be the nucleation of cytoplasmic microtubules. However, it also functions in centriole biogenesis, centriole structural integrity and ciliogenesis...
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2021) 134 (2): jcs255950.
Published: 27 January 2021
... ciliogenesis compared to wild-type cells. The cilia of cycling CDC14A KO cells are longer, whereas CDC14B KO cilia are more frequent and disassemble faster. In conclusion, this study demonstrates that the cell cycle functions of CDC14 proteins are not conserved between yeast and human cells. We thank Dr...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2021) 134 (2): jcs249565.
Published: 22 January 2021
...Mariagrazia Partisani; Carole L. Baron; Rania Ghossoub; Racha Fayad; Sophie Pagnotta; Sophie Abélanet; Eric Macia; Frédéric Brau; Sandra Lacas-Gervais; Alexandre Benmerah; Frédéric Luton; Michel Franco ABSTRACT Ciliogenesis is a coordinated process initiated by the recruitment and fusion of pre...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2019) 132 (22): jcs233973.
Published: 14 November 2019
...Shuwei Xie; Trey Farmer; Naava Naslavsky; Steve Caplan ABSTRACT The endocytic protein EHD1 plays an important role in ciliogenesis by facilitating fusion of the ciliary vesicle and removal of CP110 (also known as CCP110) from the mother centriole, as well as removal of Cep215 (also known...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2019) 132 (22): jcs233973.
Published: 14 November 2019
...Shuwei Xie; Trey Farmer; Naava Naslavsky; Steve Caplan ABSTRACT The endocytic protein EHD1 plays an important role in ciliogenesis by facilitating fusion of the ciliary vesicle and removal of CP110 (also known as CCP110) from the mother centriole, as well as removal of Cep215 (also known...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2018) 131 (16): jcs218487.
Published: 17 August 2018
... that the outer nuclear membrane protein Syne-2 (also known as Nesprin-2) is an interaction partner of Pcnt in photoreceptors. Syne-2 is important for positioning murine photoreceptor cell nuclei and for centrosomal migration during early ciliogenesis. CRISPR/Cas9-mediated knockout of Syne-2 in cell culture led...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2018) 131 (16): jcs218487.
Published: 17 August 2018
... that the outer nuclear membrane protein Syne-2 (also known as Nesprin-2) is an interaction partner of Pcnt in photoreceptors. Syne-2 is important for positioning murine photoreceptor cell nuclei and for centrosomal migration during early ciliogenesis. CRISPR/Cas9-mediated knockout of Syne-2 in cell culture led...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2018) 131 (1): jcs208769.
Published: 8 January 2018
... on primary cilium formation. Glucose deprivation significantly increased the number of ciliated cells under both serum-fed and -starved conditions. Glucose deprivation-induced ciliogenesis was suppressed by overexpression of Rheb, an activator of the mammalian target of rapamycin complex-1 (mTORC1...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2018) 131 (1): jcs208769.
Published: 8 January 2018
... on primary cilium formation. Glucose deprivation significantly increased the number of ciliated cells under both serum-fed and -starved conditions. Glucose deprivation-induced ciliogenesis was suppressed by overexpression of Rheb, an activator of the mammalian target of rapamycin complex-1 (mTORC1...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2017) 130 (8): 1450–1462.
Published: 15 April 2017
...- and cilium-related processes, including protein trafficking to the centrosome and cilium complex, and ciliogenesis, and they are implicated in ciliopathies. Despite the important regulatory roles of centriolar satellites in the assembly and function of the centrosome and cilium complex, the molecular...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2017) 130 (8): 1450–1462.
Published: 15 April 2017
...- and cilium-related processes, including protein trafficking to the centrosome and cilium complex, and ciliogenesis, and they are implicated in ciliopathies. Despite the important regulatory roles of centriolar satellites in the assembly and function of the centrosome and cilium complex, the molecular...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2016) 129 (20): 3732–3743.
Published: 15 October 2016
... reveals that cilium structure is perturbed during development, but that cilia are largely structurally and functionally normal by adulthood. Ciliogenesis MKS module Sensory cilia Transition zone Cilia and flagella are microtubule (MT)-based extensions of the plasma membrane present...
Includes: Supplementary data
Journal Articles
In collection:
Cilia and flagella
J Cell Sci (2016) 129 (20): 3732–3743.
Published: 15 October 2016
... structure is perturbed during development, but that cilia are largely structurally and functionally normal by adulthood. Ciliogenesis MKS module Sensory cilia Transition zone Biotechnology and Biological Sciences Research Council 10.13039/501100000268 Wellcome Trust 10.13039...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (12): 2289–2295.
Published: 15 June 2016
... and ciliogenesis. These findings have greatly enriched our understanding of the roles of CYLD in physiological and pathological conditions. Here, we focus on recent literature that shows how CYLD impacts on microtubule properties and functions in various biological processes, and discuss the challenges we face...
Journal Articles