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Keywords: Chromosome instability
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Journal Articles
J Cell Sci (2021) 134 (15): jcs249763.
Published: 03 August 2021
... of the methyltransferases Suv39 and Suv420 compromises localization of Aurora B kinase and corrupts mitotic chromosome segregation. Centromere Mitosis Chromosome instability Richard and Susan Smith Family Foundation http://dx.doi.org/10.13039/100001341 Division of Cancer Prevention, National...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (2): 508–520.
Published: 15 January 2013
...@biken.osaka-u.ac.jp ) 21 11 2012 © 2013. Published by The Company of Biologists Ltd 2013 Lats1 Hippo Lats2 YAP Chromosome instability Aberrant cell growth and chromosomal instability (CIN), two major hallmarks of human malignant cancer cells ( Hanahan and Weinberg, 2011...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (14): 3281–3292.
Published: 15 July 2012
... with chromosome instability (CIN). As a result, a link between centrosome amplification and cancer can be easily established ( Doxsey, 2002 ; Guo et al., 2007 ; Lingle and Salisbury, 1999 ; Lingle and Salisbury, 2000 ; Nigg, 2006 ; Zyss and Gergely, 2009 ). Importantly, however, we should also take...
Journal Articles
J Cell Sci (2010) 123 (21): 3768–3779.
Published: 01 November 2010
... Kinetochore Mitosis Chromosome instability Cal1 The centromeric regions of chromosomes direct formation of kinetochores, which allow chromosome attachment to spindle microtubules. Centromeres and kinetochores are therefore of paramount importance for faithful propagation of genetic information...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2007) 120 (19): 3327–3335.
Published: 01 October 2007
... cancer Chromosome instability Cell migration Cell adhesion β-catenin Asef IQGAP1 Actin EB1 Microtubules Finally, recent studies show that APC can inhibit β-catenin/TCF-dependent transcription through a direct interaction with a repressor complex. APC binds to βTrCP and transcriptional...
Journal Articles
J Cell Sci (2006) 119 (8): 1483–1493.
Published: 15 April 2006
... is also associated with structural chromosomal instability. * Author for correspondence (e-mail: j.frampton@bham.ac.uk ) 4 1 2006 © The Company of Biologists Limited 2006 2006 B-Myb Megakaryocytes S phase Endoreplication Transcriptional regulation Replication Genome...