... and genome organization dynamics through the cell cycle. Cell cycle Chromatin folding Nuclear genome organization In the late 19th and early 20th centuries, the concept of chromosomes occupying distinct sub-volumes or territories in interphase nuclei began to take hold ( Boveri, 1909 ; Rabl...

... 05 1998 02 04 1998 © 1998 by Company of Biologists 1998 Chromatin fiber Chromatin folding Nucleosome Eukaryotic chromatin is organized according to various hierarchical levels of DNA folding ( Wolffe, 1995 ; Koshland and Strunnikov, 1996 ). The fundamental structural...

.... Struct. Dyn . 7 , 1 – 18 . 10.1080/07391102.1989.10507747 Widom , J. ( 1989 ). Toward a unified model of chromatin folding . Annu. Rev. Biophys. Biophys. Chem . 18 , 365 – 395 . 10.1146/annurev.bb.18.060189.002053 Widom , J. and Klug , A. ( 1985 ). Structure...