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Keywords: Chondrogenesis
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Journal Articles
J Cell Sci (2020) 133 (16): jcs246934.
Published: 21 August 2020
... differentiation factor-5 enhances in vitro mesenchymal stromal cell chondrogenesis and hypertrophy . Stem Cells Dev.   22 , 1968 - 1976 . 10.1089/scd.2012.0282 Date , T. , Doiguchi , Y. , Nobuta , M. and Shindo , H. ( 2004 ). Bone morphogenetic protein-2 induces differentiation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (11): 2145–2155.
Published: 01 June 2016
...Timothy P. Rutkowski; Anat Kohn; Deepika Sharma; Yinshi Ren; Anthony J. Mirando; Matthew J. Hilton ABSTRACT RBPjκ-dependent Notch signaling regulates multiple processes during cartilage development, including chondrogenesis, chondrocyte hypertrophy and cartilage matrix catabolism. Select members...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (12): 2328–2339.
Published: 15 June 2015
... and prohibits Wnt-induced tumorigenesis . PLoS ONE   8 , e56644 . 10.1371/journal.pone.0056644 Maruyama , T. , Jiang , M. and Hsu , W. ( 2013b ). Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development . J. Bone...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (20): 4420–4428.
Published: 15 October 2014
... in chondrogenesis cause chondrodysplasias and other skeletal defects. Using mesenchymal stem cells (MSCs) in an in vitro chondrogenesis assay, we found that knockdown of the diastrophic dysplasia (DTD) sulfate transporter (DTDST, also known as SLC26A2), which is required for normal cartilage development, blocked...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (24): 6071–6083.
Published: 15 December 2012
... formation of the hypertrophic zone in mutant humeri. In micromass cultures of Prrx1-Cre Shox2 mutant limb cells, we find that Shox2 deletion in undifferentiated mesenchymal cells results in increased BMP activity that enhances early chondrogenesis, but is insufficient to provoke chondrocyte maturation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (16): 3703–3712.
Published: 15 August 2012
...@princeton.edu ) © 2012. Published by The Company of Biologists Ltd 2012 Fibronectin Chondrogenesis Stem cell differentiation Extracellular matrix, SOX9 The extracellular matrix (ECM) is a fibrillar network of proteins that has an essential role in determining tissue architecture by providing...
Journal Articles
J Cell Sci (2010) 123 (21): 3780–3788.
Published: 01 November 2010
...Yoko Takigawa; Kenji Hata; Shuji Muramatsu; Katsuhiko Amano; Koichiro Ono; Makoto Wakabayashi; Akio Matsuda; Kenji Takada; Riko Nishimura; Toshiyuki Yoneda Sox9 is an essential transcription factor for chondrogenesis by regulating the expression of chondrogenic genes. However, its regulatory...
Journal Articles
J Cell Sci (2009) 122 (20): 3627–3637.
Published: 15 October 2009
..., Wnt7a, Wnt9a and Wnt11. Moreover, Wif-1 was able to block Wnt3a-mediated activation of the canonical Wnt signalling pathway. Consequently, Wif-1 impaired growth of mesenchymal precursor cells and neutralised Wnt3a-mediated inhibition of chondrogenesis in micromass cultures of embryonic chick limb-bud...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (5): 849–857.
Published: 01 March 2007
... initial cellular condensation, whereas RECK knockdown suppressed the later ECM accumulation in the cartilaginous nodules. These results suggest that RECK expression at the right place (in the core of the nodules) and at the right time (only in the later phase) is important for proper chondrogenesis...
Includes: Supplementary data
Journal Articles
J Cell Sci (2003) 116 (14): 2885–2893.
Published: 15 July 2003
...Andrea D. Weston; Arthur V. Sampaio; Alan G. Ridgeway; T. Michael Underhill Signaling through the p38 mitogen-activated protein kinases (MAPKs) is essential for cartilage formation in primary cultures of limb mesenchyme. Here we show that, concurrent with a decrease in chondrogenesis, inhibition...
Journal Articles
J Cell Sci (2003) 116 (14): 2949–2955.
Published: 15 July 2003
...', they undergo chondrogenesis and form a tissue that is morphologically and biochemically defined as cartilage. Here, we show that dual chondro-osteogenic differentiation can be obtained in the same micromass culture of human bone-marrow stromal cells. Human bone-marrow stromal cells were pellet cultured for 4...
Journal Articles
J Cell Sci (2002) 115 (23): 4617–4628.
Published: 01 December 2002
...@molbio.mu-luebeck.de ) 11 9 2002 © The Company of Biologists Limited 2002 2002 Mouse embryonic stem cells Chondrogenesis Osteogenesis Mesenchymal cells Dedifferentiation Redifferentiation The development of the vertebrate skeleton is a multistep process that involves lineage...