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Keywords: Cholangiocytes
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Journal Articles

Hepatic biliary epithelial cells acquire epithelial integrity but lose plasticity to differentiate into hepatocytes in vitro during development

Naoki Tanimizu, Yukio Nakamura, Norihisa Ichinohe, Toru Mizuguchi, Koichi Hirata, Toshihiro Mitaka
Journal: Journal of Cell Science
J Cell Sci (2013) 126 (22): 5239–5246.
https://doi.org/10.1242/jcs.133082
Published: 15 November 2013
... they are fixed in their lineage. Here we show that epithelial cells alter their plasticity during postnatal development by examining the differentiation potential of epithelial cell adhesion molecule (EpCAM) + cholangiocytes (biliary epithelial cells) isolated from neonatal and adult mouse livers. We found...
View article titled, Hepatic biliary epithelial cells acquire epithelial integrity but lose plasticity to differentiate into hepatocytes in vitro during development
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Includes: Supplementary data