... to a membrane-bound chloride channel. CLIC1, a member of this family, is found in the cytoplasm or in internal and plasma membranes, with membrane relocalisation linked to endothelial disfunction, tumour proliferation and metastasis. The molecular switch promoting CLIC1 activation remains under investigation...

... © The Company of Biologists Limited 2007 2007 CLIC4 Chloride channel PKC Calcium Differentiation Keratinocytes AP1 The CLIC family of chloride intracellular channels is composed of seven differentially expressed proteins that localize to the cytoplasm and intracellular organelles...

.... and Shears, S. B. ( 2002 ). Regulation of calcium-activated chloride channels by inositol 3,4,5,6-tetrakisphosphate. In Current Topics in Membranes 53 (ed. C. M. Fuller), pp. 345 -363. London: Academic Press. Ho, M. W. Y., Kaetzel, M. A., Armstrong, D. L. and Shears, S. B. ( 2001 ). Regulation...

... of Biologists Limited 2002 2002 Membrane capacitance FM1-43 Exocytosis Endocytosis SNARE proteins Trafficking Chloride channel Voltage clamp It is not surprising that many layers of regulation exist for ubiquitous proteins such as ion channels as they play central roles in inter...

... in response to elevations in intracellular cAMP. * Author for correspondence (e-mail: benos@phybio.bhs.uab.edu ) 28 08 1995 16 03 1996 © 1996 by Company of Biologists 1996 Chloride channel Cystic fibrosis Colonic epithelia The acute recruitment of transport proteins...

..., the apical membrane of CF airway epithelia is Cl − -impermeable, a defect that probably contributes to the pathogenesis of the disease. © The Company of Biologists Limited 1993 1993 cystic fibrosis chloride channel processing trafficking apical membrane Journal of Cell Science, Supplement 17...

... of glycolipids and asialogangliosides are potential Pseudomonas receptors. * Author for correspondence © The Company of Biologists Limited 1993 1993 chloride channel Golgi acidification cystic fibrosis sialyl transferase Journal o f Cell Science, Supplem ent 17, 229-233 (1993) Printed in G...