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Keywords: Centriolar linker
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Journal Articles
Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction
Open AccessTara Hardy, Miseon Lee, Rebecca S. Hames, Suzanna L. Prosser, Donna-Marie Cheary, Mugdha D. Samant, Francisca Schultz, Joanne E. Baxter, Kunsoo Rhee, Andrew M. Fry
Journal:
Journal of Cell Science
J Cell Sci (2014) 127 (11): 2493–2506.
Published: 1 June 2014
... of this interaction, and potentially upon loss of oligomerization and association with rootletin, the integrity of the centriolar linker is broken and centrosomes are free to separate and establish the opposing poles of the mitotic spindle ( Fig. 8 ). Fig. 7. C-Nap1 phosphorylation disturbs its interaction...
Includes: Supplementary data
