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Keywords: Cell-cell adhesion
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Journal Articles
Journal Articles
J Cell Sci (2023) 136 (12): jcs260104.
Published: 14 June 2023
...Gillian DeWane; Nicholas M. Cronin; Logan W. Dawson; Christy Heidema; Kris A. DeMali ABSTRACT Vinculin is an actin-binding protein present at cell–matrix and cellcell adhesions, which plays a critical role in bearing force experienced by cells and dissipating it onto the cytoskeleton. Recently, we...
Includes: Supplementary data
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J Cell Sci (2019) 132 (18): jcs226753.
Published: 26 September 2019
.... It is also unclear how cellular forces, cellcell adhesion and velocities are coordinated within streams. To independently tune stiffness and collagen fiber length, we developed new hydrogels and discovered invasion-like streaming of normal epithelial cells on soft substrates coated with long collagen fibers...
Includes: Supplementary data
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Mechanobiology
J Cell Sci (2018) 131 (12): jcs211334.
Published: 27 June 2018
...Nivetha Kannan; Vivian W. Tang ABSTRACT Actomyosin II contractility in epithelial cell plays an essential role in tension-dependent adhesion strengthening. One key unsettling question is how cellular contraction transmits force to the nascent cellcell adhesion when there is no stable attachment...
Includes: Supplementary data
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J Cell Sci (2017) 130 (23): 3965–3974.
Published: 1 December 2017
... (srGAPs), which are highly conserved proteins that interact with the plasma membrane, regulate Rho family GTPases, and function in a wide range of cell biological processes. Slit–Robo GAP Brain evolution srGAP2 C. elegans Cellcell adhesion Contact inhibition National Institutes...
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J Cell Sci (2012) 125 (24): 6084–6093.
Published: 15 December 2012
... kinases of the erbB and Eph families. ADAM10-mediated cleavage of ephrins, the ligands for Eph receptors, is suggested to control Eph/ephrin-mediated cell-cell adhesion and segregation, important during normal developmental processes, and implicated in tumour neo-angiogenesis and metastasis. We previously...
Includes: Supplementary data
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J Cell Sci (2012) 125 (14): 3310–3319.
Published: 15 July 2012
... the involvement of radixin in these processes. Here we show that radixin is required for migration of PC3 prostate cancer cells, and that radixin, but not ezrin or moesin, depletion by RNA interference increases cell spread area and cellcell adhesion mediated by adherens junctions. Radixin depletion also alters...
Includes: Multimedia, Supplementary data
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Journal Articles
J Cell Sci (2010) 123 (15): 2640–2648.
Published: 1 August 2010
... is dispensable for postnatal skeletal growth, it favors osteogenesis over adipogenesis. Deletion of either cadherin reduces β-catenin abundance and β-catenin-dependent gene expression, whereas N-cadherin loss disrupts cell-cell adhesion more severely than loss of cadherin 11. Thus, Cdh2 and Cdh11 are crucial...
Journal Articles
J Cell Sci (2009) 122 (7): 905–911.
Published: 1 April 2009
... the wound, a process that appears to depend on the formation of new cell–extracellular-matrix adhesions as cells spread into the wound. In direct contrast to scrape-wounded cells, isolated cells without cell-cell contacts failed to polarize, suggesting that asymmetry of cell-cell adhesions resulting from...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (7): 933–938.
Published: 1 April 2008
...Encarnación Lozano; Marieke A. M. Frasa; Katarzyna Smolarczyk; Ulla G. Knaus; Vania M. M. Braga E-cadherin cell-cell adhesion plays a major role in the maintenance of the morphology and function of epithelial tissues. Modulation of E-cadherin function is an important process in morphogenesis...
Includes: Supplementary data
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J Cell Sci (2007) 120 (16): 2944–2952.
Published: 15 August 2007
...-mail: [email protected] ) 12 6 2007 © The Company of Biologists Limited 2007 2007 Delta Cell-cell adhesion Epidermis Stem cell Syntenin The epidermis, which forms the outer covering of mammalian skin, is maintained throughout life by proliferation of stem cells...