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1-17 of 17
Keywords: Cell signalling
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Journal Articles
Abigail Pearce, Theo Redfern-Nichols, Edward Wills, Matthew Rosa, Iga Manulak, Claudia Sisk, Xianglin Huang, Peace Atakpa-Adaji, David L. Prole, Graham Ladds
Journal:
Journal of Cell Science
J Cell Sci (2025) 138 (1): JCS263434.
Published: 15 January 2025
... IP 3 Ca 2+ signalling Cell signalling BRET FRET Biotechnology and Biological Sciences Research Council http://dx.doi.org/10.13039/501100000268 BB/Y513817/1 BB/W014831/1 BB/V509334/1 Leverhulme Trust http://dx.doi.org/10.13039/501100000275 RPG-2023-130...
Journal Articles
In collection:
Cell biology and disease
Rachael C. L. Smith, Georgios Kanellos, Nikola Vlahov, Constantinos Alexandrou, Anne E. Willis, John R. P. Knight, Owen J. Sansom
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (1): jcs248476.
Published: 13 January 2021
... cancers. This article discusses the role of translation initiation in cancer, including recent advances detailing new targets and therapeutic opportunities. Cancer Cell signalling Translation In healthy cells, control of translation initiation is required for homeostasis, which is mediated...
Includes: Supplementary data
Journal Articles
In collection:
Cell biology and disease
Rachel Caines, Amy Cochrane, Sophia Kelaini, Marta Vila-Gonzalez, Chunbo Yang, Magdalini Eleftheriadou, Arya Moez, Alan W. Stitt, Lingfang Zeng, David J. Grieve, Andriana Margariti
Journal:
Journal of Cell Science
J Cell Sci (2019) 132 (16): jcs230276.
Published: 15 August 2019
... QKI isoforms hold key roles in alternative splicing facilitating the production of vascular cells for therapy and disease modelling. Vascular smooth muscle cell Cellular reprogramming Cell signalling Stem cells Revascularisation British Heart Foundation 10.13039/501100000274 FS...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2015) 128 (7): 1408–1421.
Published: 1 April 2015
.../dbio.1997.8566 Freeman S. D. , Moore W. M. , Guiral E. C. , Holme A. D. , Turnbull J. E. , Pownall M. E. ( 2008 ). Extracellular regulation of developmental cell signaling by XtSulf1. Dev. Biol. 320 , 436 – 445 . 10.1016/j.ydbio.2008.05.554 Gilchrist...
Includes: Supplementary data
Journal Articles
George Damoulakis, Laure Gambardella, Kent L. Rossman, Campbell D. Lawson, Karen E. Anderson, Yoshinori Fukui, Heidi C. Welch, Channing J. Der, Len R. Stephens, Phillip T. Hawkins
Journal:
Journal of Cell Science
J Cell Sci (2014) 127 (11): 2589–2600.
Published: 1 June 2014
.... 10 03 2014 12 03 2014 © 2014. Published by The Company of Biologists Ltd 2014 Cell signalling Cell migration NADPH oxidase Neutrophil Rho GEF Small GTPase Rac proteins (Rac1, Rac2 and Rac3), a subgroup within the Rho family of small GTPases, regulate key aspects...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2014) 127 (2): 267–275.
Published: 15 January 2014
... that are implicated in cell adhesion, cell polarity and migration. Increasing evidence suggests that the regulation of cell signalling and the cytoskeleton by ERM proteins is crucial during cancer progression. Thus, both their expression levels and subcellular localisation would affect tumour progression. High...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2013) 126 (9): 1913–1921.
Published: 1 May 2013
...Kevin A. Janes; Douglas A. Lauffenburger Summary Computational models of cell signalling are perceived by many biologists to be prohibitively complicated. Why do math when you can simply do another experiment? Here, we explain how conceptual models, which have been formulated mathematically, have...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2013) 126 (6): 1416–1428.
Published: 15 March 2013
...Madhu Mahankali; Karen M. Henkels; Julian Gomez-Cambronero Summary Phospholipase D2 (PLD2) is a cell-signaling molecule that bears two activities: a guanine-nucleotide exchange factor (GEF) and a lipase that reside in the PX/PH domains and in two HKD domains, respectively. Upon cell stimulation...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2012) 125 (13): 3153–3163.
Published: 1 July 2012
... on phosphoinositides and controlled by PDK1 and PLCγ1. * Author for correspondence ( [email protected] ) 20 2 2012 © 2012. Published by The Company of Biologists Ltd 2012 Cell invasion Cell signalling 3-Phosphoinositide-dependent protein kinase-1 Phosphoinositide 3-kinase Phospholipase...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2012) 125 (4): 807–815.
Published: 15 February 2012
...Stephen W. G. Tait; Douglas R. Green Mitochondria have long been considered as crucial organelles, primarily for their roles in biosynthetic reactions such as ATP synthesis. However, it is becoming increasingly apparent that mitochondria are intimately involved in cell signalling pathways...
Journal Articles
Ciaran Richardson, Fatema H. Rafiqi, Håkan K. R. Karlsson, Ntsane Moleleki, Alain Vandewalle, David G. Campbell, Nick A. Morrice, Dario R. Alessi
Journal:
Journal of Cell Science
J Cell Sci (2008) 121 (5): 675–684.
Published: 1 March 2008
... for correspondence (e-mail: [email protected] ) 30 11 2007 © The Company of Biologists Limited 2008 2008 Cell signalling Kinase OSR1 SPAK WNK1 Cotransporter The STE20/SPS1-related proline/alanine-rich kinase (SPAK, STK39) and oxidative-stress-responsive kinase-1 (OSR1...
Journal Articles
Gavin I. Welsh, Sophie E. Leney, Bethan Lloyd-Lewis, Matthew Wherlock, Andrew J. Lindsay, Mary W. McCaffrey, Jeremy M. Tavaré
Journal:
Journal of Cell Science
J Cell Sci (2007) 120 (23): 4197–4208.
Published: 1 December 2007
... GLUT4 Glucose Insulin Intracellular trafficking AS160 Cell signalling Rab protein Scaffold protein Insulin regulates uptake of glucose into adipose tissue and muscle by promoting the rapid translocation of the insulin-responsive isoform of the glucose transporter, GLUT4, from...
Includes: Supplementary data
Journal Articles
Alessia Calzolari, Carla Raggi, Silvia Deaglio, Nadia Maria Sposi, Marit Stafsnes, Katia Fecchi, Isabella Parolini, Fabio Malavasi, Cesare Peschle, Massimo Sargiacomo, Ugo Testa
Journal:
Journal of Cell Science
J Cell Sci (2006) 119 (21): 4486–4498.
Published: 1 November 2006
... to investigate exosomes released by HepG2 and K562 cells into culture medium. TfR2, CD81 and to a lesser extent caveolin-1, were found to be part of the exosomal budding vesicles. In conclusion, the present study indicates that TfR2 localizes in LDTI microdomains, where it promotes cell signalling...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2004) 117 (6): 881–887.
Published: 22 February 2004
... 2003 © The Company of Biologists Limited 2004 2004 Calcium waves Gap junctions Cell signalling Connexin Gap junctional communication allows cells to share information in the form of aqueous solutes, and to respond to signals as a group rather than as individuals. The coordination...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2003) 116 (16): 3387–3397.
Published: 15 August 2003
... Superoxide Cell signalling Dictyostelium discoideum Superoxide dismutase Eukaryotic organisms employ sophisticated signalling networks to organise cellular functions. These consist of proteins with specialised enzyme activities and binding affinities, as well as smaller freely diffusible ions...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2000) 113 (23): 4151–4156.
Published: 1 December 2000
... and in bioinformatics, that allow meaningful knowledge to be extracted from all this information. 07 11 2000 © 2000 by Company of Biologists 2000 DNA microarrays Gene expression Cell biology Cell signalling Cancer During the five years or so since their introduction for use in gene...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2000) 113 (5): 759–766.
Published: 1 March 2000
...Angelika A. Noegel; Michael Schleicher ABSTRACT Actin-binding proteins are effectors of cell signalling and coordinators of cellular behaviour. Research on the Dictyostelium actin cytoskeleton has focused both on the elucidation of the function of bona fide actin-binding proteins as well...