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Keywords: Cell signalling
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Journal Articles
Journal Articles
J Cell Sci (2021) 134 (1): jcs248476.
Published: 13 January 2021
... cancers. This article discusses the role of translation initiation in cancer, including recent advances detailing new targets and therapeutic opportunities. Cancer Cell signalling Translation In healthy cells, control of translation initiation is required for homeostasis, which is mediated...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2015) 128 (7): 1408–1421.
Published: 1 April 2015
.../dbio.1997.8566 Freeman   S. D. , Moore   W. M. , Guiral   E. C. , Holme   A. D. , Turnbull   J. E. , Pownall   M. E. ( 2008 ). Extracellular regulation of developmental cell signaling by XtSulf1.   Dev. Biol.   320 , 436 – 445 . 10.1016/j.ydbio.2008.05.554 Gilchrist...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2014) 127 (2): 267–275.
Published: 15 January 2014
... that are implicated in cell adhesion, cell polarity and migration. Increasing evidence suggests that the regulation of cell signalling and the cytoskeleton by ERM proteins is crucial during cancer progression. Thus, both their expression levels and subcellular localisation would affect tumour progression. High...
Journal Articles
J Cell Sci (2013) 126 (9): 1913–1921.
Published: 1 May 2013
...Kevin A. Janes; Douglas A. Lauffenburger Summary Computational models of cell signalling are perceived by many biologists to be prohibitively complicated. Why do math when you can simply do another experiment? Here, we explain how conceptual models, which have been formulated mathematically, have...
Journal Articles
Journal Articles
J Cell Sci (2012) 125 (13): 3153–3163.
Published: 1 July 2012
... on phosphoinositides and controlled by PDK1 and PLCγ1. * Author for correspondence ( [email protected] ) 20 2 2012 © 2012. Published by The Company of Biologists Ltd 2012 Cell invasion Cell signalling 3-Phosphoinositide-dependent protein kinase-1 Phosphoinositide 3-kinase Phospholipase...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (4): 807–815.
Published: 15 February 2012
...Stephen W. G. Tait; Douglas R. Green Mitochondria have long been considered as crucial organelles, primarily for their roles in biosynthetic reactions such as ATP synthesis. However, it is becoming increasingly apparent that mitochondria are intimately involved in cell signalling pathways...
Journal Articles
Journal Articles
J Cell Sci (2007) 120 (23): 4197–4208.
Published: 1 December 2007
... GLUT4 Glucose Insulin Intracellular trafficking AS160 Cell signalling Rab protein Scaffold protein Insulin regulates uptake of glucose into adipose tissue and muscle by promoting the rapid translocation of the insulin-responsive isoform of the glucose transporter, GLUT4, from...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2004) 117 (6): 881–887.
Published: 22 February 2004
... 2003 © The Company of Biologists Limited 2004 2004 Calcium waves Gap junctions Cell signalling Connexin Gap junctional communication allows cells to share information in the form of aqueous solutes, and to respond to signals as a group rather than as individuals. The coordination...
Journal Articles
J Cell Sci (2003) 116 (16): 3387–3397.
Published: 15 August 2003
... Superoxide Cell signalling Dictyostelium discoideum Superoxide dismutase Eukaryotic organisms employ sophisticated signalling networks to organise cellular functions. These consist of proteins with specialised enzyme activities and binding affinities, as well as smaller freely diffusible ions...
Journal Articles
J Cell Sci (2000) 113 (23): 4151–4156.
Published: 1 December 2000
... and in bioinformatics, that allow meaningful knowledge to be extracted from all this information. 07 11 2000 © 2000 by Company of Biologists 2000 DNA microarrays Gene expression Cell biology Cell signalling Cancer During the five years or so since their introduction for use in gene...
Journal Articles
J Cell Sci (2000) 113 (5): 759–766.
Published: 1 March 2000
...Angelika A. Noegel; Michael Schleicher ABSTRACT Actin-binding proteins are effectors of cell signalling and coordinators of cellular behaviour. Research on the Dictyostelium actin cytoskeleton has focused both on the elucidation of the function of bona fide actin-binding proteins as well...