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Keywords: Cell polarity
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Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2022) 135 (4): jcs259228.
Published: 16 February 2022
...Shengnan Zheng; Biyu Zheng; Zhenbang Liu; Xiaopeng Ma; Xing Liu; Xuebiao Yao; Wenfan Wei; Chuanhai Fu ABSTRACT Septins are a family of filament-forming GTP-binding proteins that regulate fundamental cellular activities, such as cytokinesis and cell polarity. In general, septin filaments function...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (11): jcs240283.
Published: 11 June 2020
...://www.biologists.com/user-licence-1-1/ Summary: The Cdc42 guanine-nucleotide-exchange factor Cdc24 interacts with septins during bud site assembly. This interaction assists in recruiting septins and stabilizing Cdc24 at the incipient bud site. Cell polarity Protein–protein interaction SPLIFF Positive...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (17): jcs231720.
Published: 2 September 2019
... http://www.biologists.com/user-licence-1-1/ Summary: ATP11C-b, a C-terminal splice variant of the PS-flippase ATP11C, localizes to a limited region of the plasma membrane in polarized cells, and LLXY residues are critical for the localization. Cell polarity Membrane lipids Transporters...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (14): jcs230714.
Published: 15 July 2019
... signaling hubs to promote cell polarization and actin nucleation. Here, we probe the nature of these domains using a variety of membrane- and actin cortex-associated probes. These data demonstrate that these domains are filopodia, which are stimulated transiently during polarity establishment and accumulate...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (12): jcs224501.
Published: 17 June 2019
...Indrasen Magre; Vikas Fandade; Indraneel Damle; Poulomi Banerjee; Santosh Kumar Yadav; Mahendra Sonawane; Jomon Joseph ABSTRACT The Par polarity complex, consisting of Par3, Par6 and atypical protein kinase C (aPKC), plays a crucial role in the establishment and maintenance of cell polarity...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (11): jcs230706.
Published: 31 May 2019
... on chemoattractant gradient detection in yeast, which occurs at a motile polarity patch. It further describes the stabilization and hyperpolarization process underlying cell fusion. Cell fusion Cell polarity Chemotropism Pheromone gradient Cdc42 MAPK S. cerevisiae S. pombe All cells...
Journal Articles
In collection:
Polarity
J Cell Sci (2019) 132 (8): jcs225243.
Published: 15 April 2019
..., Industria y Competitividad grants BFU2012-38191 and BFU2015-65685-P. References Ahringer , J. ( 2003 ). Control of cell polarity and mitotic spindle positioning in animal cells . Curr. Opin. Cell Biol.   15 , 73 - 81 . 10.1016/S0955-0674(02)00018-2 Asnacios , A. and Hamant...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (4): jcs217554.
Published: 30 January 2019
...Kim J. A. Vendel; Sophie Tschirpke; Fayezeh Shamsi; Marileen Dogterom; Liedewij Laan ABSTRACT Cell polarity – the morphological and functional differentiation of cellular compartments in a directional manner – is required for processes such as orientation of cell division, directed cellular growth...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (20): jcs221853.
Published: 17 October 2018
..., also known as STK10) or Ste20-like kinase (SLK). We also discuss how ezrin-binding scaffolding proteins regulate microvilli and how, despite these significant advances, it remains to be discovered how the cell polarity program ultimately interfaces with these processes. References Anniko , M...
Journal Articles
In collection:
Polarity
J Cell Sci (2018) 131 (14): jcs216580.
Published: 19 July 2018
...Ye Dee Tay; Marcin Leda; Andrew B. Goryachev; Kenneth E. Sawin ABSTRACT The conserved Rho-family GTPase Cdc42 plays a central role in eukaryotic cell polarity. The rod-shaped fission yeast Schizosaccharomyces pombe has two Cdc42 guanine nucleotide exchange factors (GEFs), Scd1 and Gef1, but little...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (11): jcs213199.
Published: 11 June 2018
... their apical cell surface delivery to promote accurate tubulocyst formation. Galectin-3 β1-integrin Apical transport Endocytosis Cell polarity Epithelial cells maintain a polarized structure in which the apical membrane domain is separated by a tight junctional complex from the basolateral...
Includes: Supplementary data
Journal Articles
In collection:
Polarity
J Cell Sci (2018) 131 (6): jcs214015.
Published: 26 March 2018
... ). TRACMIT: an effective pipeline for tracking and analyzing cells on micropatterns through mitosis . PLoS ONE   12 , e0179752 . 10.1371/journal.pone.0179752 Butler , M. T. and Wallingford , J. B. ( 2017 ). Planar cell polarity in development and disease . Nat. Rev. Mol. Cell Biol.   18...
Journal Articles
In collection:
Polarity
J Cell Sci (2017) 130 (7): 1224–1231.
Published: 1 April 2017
... of the daughter cells. Since most plasma membrane proteins are glycosylated, we determined the effect of attenuation of N-glycosylation on cell polarity. While polarity establishment was not perturbed, the size difference between the two cells formed in first cell division (AB and P1) was more variable in embryos...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (1): 243–259.
Published: 1 January 2017
.... Cell polarity Epithelial Cells Tight junctions Morphogenesis Lumen Formation The ability to form and expand lumens is an essential characteristic of epithelia within tubular organs, such as kidneys and intestines, and is indispensable to their function. Such lumens are lined by a monolayer...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (22): 4252–4264.
Published: 15 November 2016
... Molecular motor Cell polarity Actin Asymmetric protein sorting underlies the establishment and maintenance of cell polarity. Recent studies have revealed that mRNA localization is a prevalent mechanism used by different cell types for restricting protein localization ( Cajigas et al., 2012...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (21): 4130–4142.
Published: 1 November 2016
... cultures ( Al-Aidaroos and Zeng, 2010 ; Rios et al., 2013 ). PRL-3 PTP4A3 Midbody Cell polarity Epithelia Cancer Summary: The cancer-promoting phosphatase PRL-3 triggers ectopic lumen formation through midbody mispositioning by accelerating cytokinesis, suggesting a new oncogenic...
Includes: Supplementary data
Journal Articles
In collection:
Imaging
J Cell Sci (2016) 129 (18): 3462–3472.
Published: 15 September 2016
... , A. and Ecke , M. ( 2012 ). PIP3 waves and PTEN dynamics in the emergence of cell polarity . Biophys. J.   103 , 1170 - 1178 . 10.1016/j.bpj.2012.08.004 Gerisch , G. , Ecke , M. , Neujahr , R. , Prassler , J. , Stengl , A. , Hoffmann , M. , Schwarz , U. S...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (9): 1915–1927.
Published: 1 May 2016
... progenitor monolayer formation and epidermal spreading are delayed in Crash mice, which possess a dominant mutation in Celsr1, an orthologue of the core planar cell polarity (PCP) Drosophila protein Flamingo (also known as Stan). We observe a failure of ventral enclosure in Crash mutants suggesting...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (11): 2106–2117.
Published: 1 June 2015
.... Cell polarity Budding pattern Computational modeling Saccharomyces cerevisiae GTPase Cell polarization generally occurs along a single axis in response to spatial cues. In the budding yeast Saccharomyces cerevisiae , the axis of polarized growth is determined by selection of a bud site...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (5): 1001–1010.
Published: 1 March 2015
...   R. H. ( 2007 ). ZBP1 enhances cell polarity and reduces chemotaxis.   J. Cell Sci.   120 , 3173 – 3178 . 10.1242/jcs.000638 Latham   V. M. , Yu   E. H. , Tullio   A. N. , Adelstein   R. S. , Singer   R. H. ( 2001 ). A Rho-dependent signaling pathway operating through...
Includes: Supplementary data