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Keywords: Cdc25
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J Cell Sci (2013) 126 (5): 1081–1085.
Published: 1 March 2013
...). PCR was performed using primers reported in supplementary material Table S1 . Oocytes were collected in phosphate-buffered saline (PBS) containing 1% polyvinylpyrrolidine (PVP) and frozen in SDS sample buffer. Western blotting was performed using antibodies against Cdc25 phosphatases (sc-65503...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (21): 5124–5137.
Published: 1 November 2012
... abrogates Cdc25 and Cdk activations in Aβ 1-42 -treated neurons. Similarly, phosphorylation-resistant mutants of Cdc25 isoforms at Cdk5 sites are defective in activating Cdk1, Cdk2 and Cdk4 in Aβ 1-42 -treated primary cortical neurons, emphasizing a major role of Cdk5 in the activation of Cdc25 isoforms...
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Journal Articles
J Cell Sci (2000) 113 (10): 1727–1736.
Published: 15 May 2000
... of Cdc25p is also insufficient to regulate checkpoint arrest. Conversely, inactivation of both wee1 + and cdc25 + abolishes checkpoint control. We also show that activation of the G 2 DNA damage checkpoint induces a transient increase in Wee1p levels. We conclude that the G 2 DNA damage checkpoint...
Journal Articles
J Cell Sci (1999) 112 (21): 3747–3756.
Published: 1 November 1999
... kinase and its activating phosphatase Cdc25 allows the abrupt activation of MPF and the entry into the first meiotic division. We have studied the Cdc2/Cdc25 feed-back loop using cell-free systems derived from Xenopus prophase-arrested oocyte. Our findings support the following two-step model for MPF...
Journal Articles
J Cell Sci (1999) 112 (18): 3137–3146.
Published: 15 September 1999
...Rafael R. Daga; Juan Jimenez ABSTRACT The eukaryotic translation initiation factor 4A (eIF4A) is an RNA helicase required for translation initiation of eukaryotic mRNAs. By engineering fission yeast mutants with diminished eIF4A activity, we have found that translation of cdc25 mRNAs (a dosage...
Journal Articles
J Cell Sci (1998) 111 (22): 3401–3410.
Published: 15 November 1998
... for correspondence 28 10 1998 19 09 1998 © 1998 by Company of Biologists 1998 Cdc25 In-gel kinase assay Lamin Microtubule Okadaic acid Mouse FT210 cell Cells undergo dramatic structural changes when they enter mitosis: their shape changes as the cytoskeleton is reorganised...
Journal Articles
J Cell Sci (1998) 111 (16): 2445–2453.
Published: 15 August 1998
...Christiane Lammer1; Sybille Wagerer; Rainer Saffrich; Daniel Mertens; Wilhelm Ansorge; Ingrid Hoffmann ABSTRACT Cdc25 phosphatases play key roles in cell cycle progression by activating cyclin-dependent kinases. In human cells, cdc25 proteins are encoded by a multigene family, consisting of cdc25A...
Journal Articles
Journal Articles
J Cell Sci (1994) 1994 (Supplement_18): 75–79.
Published: 1 January 1994
... specificity cdc25 phosphatase. © The Company of Biologists Limited 1994 1994 cdk cdc25 cell cycle phosphorylation feedback control The past five years have seen a prodigious advance in our understanding of how the cell cycle is regulated. Separate lines of studies in different organisms...
Journal Articles
J Cell Sci (1993) 106 (4): 1153–1168.
Published: 1 December 1993
... stimulates its own production by activating Cdc25 and inhibiting Wee1) and a negative feedback loop (MPF stimulates its own destruction by indirectly activating the ubiquitin pathway that degrades its cyclin subunit). To uncover the full dynamical possibilities of the control system, we translate...
Journal Articles
J Cell Sci (1993) 106 (4): 1035–1044.
Published: 1 December 1993
...Helen White-Cooper; Luke Alphey; David M. Glover ABSTRACT The twine HB5 mutation prevents spindle formation during the entry into meiosis in Drosophila males, but chromosome condensation and nuclear envelope break-down both still occur. This suggests the possibility that this particular cdc25...
Journal Articles
J Cell Sci (1992) 101 (3): 475–482.
Published: 3 January 1992
... of Public Health, Boston MA 02115, USA † Author for correspondence 21 08 1991 06 12 1991 © 1991 The Company of Biologists Ltd. 1991 mitosis cdc2 cyclin cdc25 p65 Two decades ago, Hartwell and co-workers isolated a number of cell division cycle (cdc) mutants...
Journal Articles
J Cell Sci (1991) 99 (3): 669–674.
Published: 1 July 1991
.... A database search revealed that the CDC25 and SCD25 genes of the budding yeast Saccharomyces cerevisiae also contain some of the newly identified motifs, perhaps indicating a common regulatory or degradation pathway. 11 03 1991 07 05 1991 © 1991 by Company of Biologists 1991 cell...