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Keywords: Cathepsin
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Journal Articles
J Cell Sci (2022) 135 (20): jcs259900.
Published: 19 October 2022
... role in stem cell function. However, the mechanisms that modulate the function of ECM regulators in the stem cell niche are understudied. Here, we explored the role of the transcription factor (TF) ETS-1, which is expressed in the cathepsin-positive cell population, in regulating the expression...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (17): jcs216127.
Published: 7 September 2018
.... , Ezaki , J. , Isahara , K. , Ohsawa , Y. , Schulz-Schaeffer , W. , Watanabe , T. , Waguri , S. , Kametaka , S. , et al. ( 2000 ). Cathepsin D deficiency induces lysosomal storage with ceroid lipofuscin in mouse CNS neurons . J. Neurosci.   20 , 6898 - 6906 . 10.1523...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (24): 5578–5584.
Published: 15 December 2013
... lysosomal exocytosis and apoptosis induction. UVA, but not UVB, induced plasma membrane damage, which was repaired by Ca 2+ -dependent lysosomal exocytosis. The lysosomal exocytosis resulted in extracellular release of cathepsin D and acid sphingomyelinase (aSMase). Two hours after UVA irradiation, we...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (23): 4935–4943.
Published: 1 December 2006
... proteins to lysosomes even in the absence of endosomal acidification. * Author for correspondence (e-mail: lukas.mach@boku.ac.at ) 28 9 2006 © The Company of Biologists Limited 2006 2006 Mannose 6-phosphate Lysosome Trafficking Cathepsin Hydrolase Biosynthesis...
Journal Articles
J Cell Sci (2002) 115 (24): 4877–4889.
Published: 15 December 2002
...Martin Linke; Volker Herzog; Klaudia Brix Cathepsin B, a lysosomal cysteine proteinase, is involved in limited proteolysis of thyroglobulin with thyroxine liberation at the apical surface of thyroid epithelial cells. To analyze the trafficking of lysosomal enzymes to extracellular locations...