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Keywords: Caspase-8
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Journal Articles
Christian T. Hellwig, Agnieszka H. Ludwig-Galezowska, Caoimhin G. Concannon, David W. Litchfield, Jochen H. M. Prehn, Markus Rehm
Journal:
Journal of Cell Science
J Cell Sci (2010) 123 (9): 1401–1406.
Published: 1 May 2010
...Christian T. Hellwig; Agnieszka H. Ludwig-Galezowska; Caoimhin G. Concannon; David W. Litchfield; Jochen H. M. Prehn; Markus Rehm In the present study, we quantitatively analysed the interface between apoptosis initiation and execution by determining caspase-8 activation, Bid cleavage...
Includes: Supplementary data
Journal Articles
Mariola Fotin-Mleczek, Frank Henkler, Dierk Samel, Monica Reichwein, Angelika Hausser, Ingela Parmryd, Peter Scheurich, Johannes A. Schmid, Harald Wajant
Journal:
Journal of Cell Science
J Cell Sci (2002) 115 (13): 2757–2770.
Published: 1 July 2002
... activation of caspase-8 was significantly weaker and delayed. Costimulation or prestimulation of TNF-R2 enhanced caspase-8 processing. Life cell imaging and confocal microscopy revealed that both TNF-R1 and TNF-R2 recruited the anti-apoptotic factor cIAP1 in a TRAF2-dependent manner. Thus, TNF-R2 may compete...
