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Keywords: Cardiomyocytes
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Journal Articles
J Cell Sci (2010) 123 (18): 3136–3145.
Published: 15 September 2010
...) was reported to be an actin nucleator in cardiomyocytes. Here, we have identified a function of Lmod2 in the regulation of thin filament lengths. We show that Lmod2 localizes to the pointed ends of thin filaments, where it competes for binding with tropomodulin-1 (Tmod1). Overexpression of Lmod2 results...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (5): 727–734.
Published: 1 March 2009
... is much more accessible to intact anti-HA antibody. By contrast, the Fab fragment of the anti-HA antibody could readily detect GLUT4 at the surface of both the sarcolemma and transverse tubules. Here, we have used this mouse model to examine the route taken by cardiomyocyte GLUT4 as it moves...
Journal Articles
J Cell Sci (2005) 118 (15): 3509–3521.
Published: 1 August 2005
... to various epithelial cells. To understand more about the physiological function of CAR, we have generated CAR-deficient mice by gene targeting. We found that these mice die between E11.5 and E13.5 of embryonal development. Ultrastructural analysis of cardiomyocytes revealed that the density of myofibrils...
Journal Articles
J Cell Sci (2004) 117 (3): 507–514.
Published: 22 January 2004
...Bradley W. Doble; Xitong Dang; Peipei Ping; Robert R. Fandrich; Barbara E. Nickel; Yan Jin; Peter A. Cattini; Elissavet Kardami Mitogenic stimulation of cardiomyocytes is associated with decreased gap junction coupling and protein kinase C (PKC)-mediated phosphorylation of the gap junction protein...
Journal Articles
J Cell Sci (2004) 117 (1): 105–114.
Published: 1 January 2004
..., immunofluorescence analysis of cultured embryonic chick cardiomyocytes and the targeting and phenotypic effects of these individual GFP-tagged regions of N-RAP, we proposed a novel model for the initiation of myofibril assembly in which N-RAP organizes α-actinin and actin into the premyofibril I-Z-I complexes. We...
Journal Articles
J Cell Sci (2003) 116 (24): 5005–5013.
Published: 15 December 2003
...Robert G. Kelly; Marguerite Lemonnier; Stephane Zaffran; Andrew Munk; Margaret E. Buckingham The molecular mechanisms that establish and maintain transcriptional differences between cardiomyocytes in the left and right ventricular chambers are unkown. We have previously analysed a myosin light...
Journal Articles
J Cell Sci (2003) 116 (19): 4001–4009.
Published: 1 October 2003
...Mónica Bettencourt-Dias; Sybille Mittnacht; Jeremy P. Brockes Adult newt cardiomyocytes, in contrast to their mammalian counterparts, can proliferate after injury and contribute to the functional regeneration of the heart. In order to understand the mechanisms underlying this plasticity we...
Includes: Supplementary data