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Keywords: Capping Protein
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Journal Articles
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J Cell Sci (2021) 134 (21): jcs258973.
Published: 05 November 2021
... function for the distribution of F-actin plus and minus ends. In syncytial Drosophila embryos, Rho1 signaling is high between actin caps, i.e. the cortical intercap region. Capping protein binds to free plus ends of F-actin to prevent elongation of the filament. Capping protein has served as a marker...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (6): 1085–1091.
Published: 15 March 2016
... barbed-end-interacting proteins and the kinetic mechanisms by which they regulate actin filament assembly. We take F-actin capping protein, gelsolin, profilin and barbed-end-tracking polymerases, including formins and WH2-domain-containing proteins, as examples, and illustrate how their activity...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (10): 1969–1981.
Published: 15 May 2015
...Raphaëlle Dubruille; Benjamin Loppin ABSTRACT In Drosophila , telomere-capping proteins have the remarkable capacity to recognize chromosome ends in a sequence-independent manner. This epigenetic protection is essential to prevent catastrophic ligations of chromosome extremities. Interestingly...
Journal Articles
J Cell Sci (2015) 128 (1): 160–170.
Published: 01 January 2015
...Yu-Jin Jo; Woo-In Jang; Suk Namgoong; Nam-Hyung Kim ABSTRACT Actin polymerization is essential for various stages of mammalian oocyte maturation, including spindle migration, actin cap formation, polar body extrusion and cytokinesis. The heterodimeric actin-capping protein is an essential element...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (8): 1547–1557.
Published: 15 April 2006
... to demonstrate that Twf1 severs individual actin filaments in real time. It has been shown that capping protein directly binds to Twf1 and is required for Twf1 localization to cortical actin patches in vivo. We demonstrate that capping protein directly inhibits the severing activity of Twf1, the first...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2002) 115 (24): 4721–4726.
Published: 15 December 2002
.../VASP field, pointing to roles for these proteins in both promotion and inhibition of actin-dependent processes. Recent discoveries resolve these contradictions and suggest a novel mechanism of Ena/VASP function, in which the proteins function as `anti-capping' proteins that antagonize capping proteins...
Journal Articles
J Cell Sci (2002) 115 (5): 881–886.
Published: 01 March 2002
... contributes to actin filament turnover by localizing actin monomers, in their `inactive'ADP-form, to the sites of rapid filament assembly. This is mediated through direct interactions between twinfilin and capping protein. Therefore,twinfilin might serve as a link between rapid actin filament depolymerization...
Journal Articles
J Cell Sci (2001) 114 (24): 4533–4542.
Published: 15 December 2001
... Actin Capping Protein The actin cytoskeleton is one of the primary determinants of cell shape and motility. In the process of actin cytoskeletal reorganization, the Wiskott-Aldrich syndrome protein (WASP) family plays essential roles downstream of many regulators ( Takenawa and Miki, 2001...