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Keywords: Calcium signalling
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Journal Articles
J Cell Sci (2022) 135 (2): jcs258796.
Published: 18 January 2022
.... Summary: CaM mutations associated with human cardiac arrhythmia syndromes result in CaM dysfunction, which appears to be a key driver of the disease, with different mutants acting via different mechanisms. CPVT CaMKII RyR2 Arrhythmia Calcium signalling Calmodulin British Heart...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (22): jcs221994.
Published: 19 November 2018
... receptors, we show that basal lipolysis and adipokine secretion are controlled by autocrine purinergic signalling via P2Y 2 receptors in human adipocytes. Adipose tissue Purinergic receptor Calcium signalling Human White adipose tissue (WAT) is the primary site of long-term energy storage...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (10): 2305–2313.
Published: 15 May 2013
... [grant number BB/H009736/1]. Deposited in PMC for release after 6 months. References Berridge   M. J. , Lipp   P. , Bootman   M. D. ( 2000 ). The versatility and universality of calcium signalling.   Nat. Rev. Mol. Cell Biol.   1 , 11 – 21 . 10.1038/35036035 Betzenhauser...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (23): 5636–5646.
Published: 1 December 2012
... defect similar to that found in PIPKIγ −/− mice, while agonist-induced calcium signaling was reduced in PIPKIγ −/− cells, but was not affected in the absence of PIPKIγ_i2. A reported contribution of PIPKIγ to epithelial integrity was not evident in PIPKIγ −/− mice. Given that mice lacking PIPKIγ_i2 live...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2004) 117 (26): 6289–6296.
Published: 15 December 2004
... ) 29 9 2004 © The Company of Biologists Limited 2004 2004 Calcium Calcium signalling Cell cycle proteins Fertilization Mammals Meiosis Metaphase Mice Oocytes Signal transduction Ubiquitin-protein ligases Destruction of key cell cycle proteins is coordinated...
Journal Articles
J Cell Sci (2004) 117 (8): 1567–1576.
Published: 15 March 2004
... calcium, cyclic AMP (cAMP) and multiple kinase signalling pathways. Mice with the PAF-receptor gene deleted ( Pafr –/–) ( Ishii et al., 1998 ) had an absence of surface PAF-receptors in a variety of tissues, had attenuated PAF-induced calcium signal transduction in neutrophils and displayed defects...
Journal Articles
J Cell Sci (2002) 115 (12): 2497–2504.
Published: 15 June 2002
... ) 18 3 2002 © The Company of Biologists Limited 2002 2002 Ryanodine receptor channels Calcium signalling Calcium stores Endoplasmic sarcoplasmic reticulum Calcium release The endoplasmic reticulum of most eukaryotic cells contains relatively high levels of Ca 2+ and represent...
Journal Articles
J Cell Sci (2002) 115 (9): 1869–1876.
Published: 1 May 2002
...Akihisa Segawa; Haruo Takemura; Shohei Yamashina Organ function requires coordinated multicellular activities, which may require proper control of cell signalling dynamics at the supracellular level. By using high-speed confocal microscopy, we studied how calcium signalling is organised...
Includes: Multimedia, Supplementary data