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Keywords: Cadherins
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Journal Articles
J Cell Sci (2014) 127 (12): 2603–2613.
Published: 15 June 2014
...Tim Pieters; Frans van Roy ABSTRACT Pluripotent embryonic stem cells (ESCs) can self-renew or differentiate into any cell type within an organism. Here, we focus on the roles of cadherins and catenins – their cytoplasmic scaffold proteins – in the fate, maintenance and differentiation of mammalian...
Journal Articles
J Cell Sci (2013) 126 (22): 5293–5304.
Published: 15 November 2013
...Emilie Guillaume; Franck Comunale; Nam Do Khoa; Damien Planchon; Stéphane Bodin; Cécile Gauthier-Rouvière Summary Cadherins are essential in many fundamental processes and assemble at regions of cell–cell contact in large macromolecular complexes named adherens junctions. We have identified...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (10): 2478–2485.
Published: 15 May 2012
...Matthew D. Langer; Huabei Guo; Nitesh Shashikanth; J. Michael Pierce; Deborah E. Leckband We present direct evidence that the N-glycosylation state of neural cadherin impacts the intrinsic kinetics of cadherin-mediated intercellular binding. Micropipette manipulation measurements quantified...
Journal Articles
J Cell Sci (2011) 124 (12): 2013–2020.
Published: 15 June 2011
...Peter J. B. Sabatini; Ming Zhang; Rosalind V. Silverman-Gavrila; Michelle P. Bendeck Cadherins aggregate and stabilize cell–cell junctions through interactions with adjacent cells. In addition, N-cadherin and E-cadherin concentrate at free edges or at the lamellipodia of migrating cells...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2006) 119 (9): 1801–1811.
Published: 01 May 2006
...Samantha J. Stehbens; Andrew D. Paterson; Matthew S. Crampton; Annette M. Shewan; Charles Ferguson; Anna Akhmanova; Robert G. Parton; Alpha S. Yap In contrast to the well-established relationship between cadherins and the actin cytoskeleton, the potential link between cadherins and microtubules...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (1): 66–74.
Published: 01 January 2006
...Porntula Panorchan; Melissa S. Thompson; Kelly J. Davis; Yiider Tseng; Konstantinos Konstantopoulos; Denis Wirtz Cadherins are ubiquitous cell surface molecules that are expressed in virtually all solid tissues and localize at sites of cell-cell contact. Cadherins form a large and diverse family...
Journal Articles
J Cell Sci (2005) 118 (23): 5549–5562.
Published: 01 December 2005
...Juankun Zhang; Martha Betson; Jennifer Erasmus; Kostas Zeikos; Maryse Bailly; Louise P. Cramer; Vania M. M. Braga The ability of epithelial cells to polarize requires cell-cell adhesion mediated by cadherin receptors. During cell-cell contact, the mechanism via which a flat, spread cell shape...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (20): 4765–4783.
Published: 15 October 2005
...Fiorella Balzac; Maria Avolio; Simona Degani; Irina Kaverina; Mauro Torti; Lorenzo Silengo; J. Victor Small; Saverio Francesco Retta The coordinate modulation of cadherin and integrin functions plays an essential role in fundamental physiological and pathological processes, including morphogenesis...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2004) 117 (18): 4325–4339.
Published: 15 August 2004
... and by expressing E-cadherin mutants unable to bind p120. This resulted in defective eye formation and provoked malformations in the craniofacial cartilage structures, derivatives of the cranial neural crest cells. Closer inspection showed that p120 depletion impaired evagination of the optic vesicles and migration...
Includes: Supplementary data
Journal Articles
J Cell Sci (2004) 117 (13): 2853–2864.
Published: 01 June 2004
...Charlles H. M. Castro; Chan Soo Shin; Joseph P. Stains; Su-Li Cheng; Sharmin Sheikh; Gabriel Mbalaviele; Vera Lucia Szejnfeld; Roberto Civitelli We studied the function of osteoblast cadherins in vivo by transgenic expression of a truncated N-cadherin with dominant-negative action, driven...
Journal Articles
J Cell Sci (2003) 116 (24): 4985–4995.
Published: 15 December 2003
... glycoproteins N-cadherin and cadherin-11 [which also occur in heterotypic (`mixed') complexes] are associated with α- and β-catenin, plakoglobin (proportions variable among species), p120 ctn and vinculin. The other complex contains ezrin, periplakin, periaxin and desmoyokin (and so is called the EPPD complex...
Journal Articles
J Cell Sci (2003) 116 (2): 377–386.
Published: 15 January 2003
...Elizabeth E. Robinson; Kathleen M. Zazzali; Siobhan A. Corbett; Ramsey A. Foty Integrins and cadherins are considered to have distinct and opposing functions. Integrins are traditionally cited for their role in cell-substratum interactions, whereas cadherins are thought to mediate strong...
Journal Articles
J Cell Sci (2002) 115 (23): 4505–4515.
Published: 01 December 2002
...Snježana Kutleša; Johannes T. Wessels; Angelika Speiser; Inge Steiert; Claudia A. Müller; Gerd Klein Cadherins are a family of cell adhesion molecules that mainly mediate homotypic homophilic interactions, but for E-cadherin, heterophilic interactions with the integrin α E (CD103)β 7 have also...