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... , W. and Hallett , M. B. ( 2006 ). Localised PtdIns(3,4,5)P3 or PtdIns(3,4)P2 at the phagocytic cup is required for both phagosome closure and Ca2+ signalling in HL60 neutrophils . J. Cell Sci. 119 , 443 - 451 . 10.1242/jcs.02756 Dewitt , S. , Francis , R. J...

View article titled, Ca 2+ -activated cleavage of ezrin visualised dynamically in living myeloid cells during cell surface area expansion

Includes: Supplementary data

Journal Articles

Association of cardiac myosin-binding protein-C with the ryanodine receptor channel – putative retrograde regulation?

Paulina J. Stanczyk, Monika Seidel, Judith White, Cedric Viero, Christopher H. George, Spyros Zissimopoulos, F. Anthony Lai

J Cell Sci (2018) 131 (15): jcs210443.

DOI: https://doi.org/10.1242/jcs.210443

Published: 3 August 2018

View article titled, Association of cardiac myosin-binding protein-C with the ryanodine receptor channel – putative retrograde regulation?

Includes: Supplementary data

Journal Articles

Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes

Michelle L. Munro, Isuru D. Jayasinghe, Qiongling Wang, Ann Quick, Wei Wang, David Baddeley, Xander H. T. Wehrens, Christian Soeller

J Cell Sci (2016) 129 (23): 4388–4398.

DOI: https://doi.org/10.1242/jcs.196873

Published: 1 December 2016

... - L24 . 10.1016/j.bpj.2013.02.059 Woo , J. S. , Hwang , J.-H. , Ko , J.-K. , Weisleder , N. , Kim , D. H. , Ma , J. and Lee , E. H. ( 2010 ). S165F mutation of junctophilin 2 affects Ca2+ signalling in skeletal muscle . Biochem. J. 427 , 125 - 134 . 10.1042...

View article titled, Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes

Includes: Supplementary data

Journal Articles

Mutant IP 3 receptors attenuate store-operated Ca 2+ entry by destabilizing STIM–Orai interactions in Drosophila neurons

Sumita Chakraborty, Bipan K. Deb, Tetyana Chorna, Vera Konieczny, Colin W. Taylor, Gaiti Hasan

J Cell Sci (2016) 129 (20): 3903–3910.

DOI: https://doi.org/10.1242/jcs.191585

Published: 15 October 2016

View article titled, Mutant IP 3 receptors attenuate store-operated Ca 2+ entry by destabilizing STIM–Orai interactions in Drosophila neurons

Includes: Supplementary data

Journal Articles

Ca 2+ is a key factor in α-synuclein-induced neurotoxicity

Plamena R. Angelova, Marthe H. R. Ludtmann, Mathew H. Horrocks, Alexander Negoda, Nunilo Cremades, David Klenerman, Christopher M. Dobson, Nicholas W. Wood, Evgeny V. Pavlov, Sonia Gandhi, Andrey Y. Abramov

J Cell Sci (2016) 129 (9): 1792–1801.

DOI: https://doi.org/10.1242/jcs.180737

Published: 1 May 2016

... 2 min, B). Results are mean±s.e.m. [ n =91, control; n =68, monomers (B)] Fig. 4. Monomeric α-synuclein leads to impairment of Ca2+ efflux. Application of 5 μM glutamate to cells pre-incubated with α-synuclein monomers (A) resulted in significantly delayed recovery of the cytosolic Ca2+ signal...

View article titled, Ca 2+ is a key factor in α-synuclein-induced neurotoxicity

Journal Articles

Sustained signalling by PTH modulates IP 3 accumulation and IP 3 receptors through cyclic AMP junctions

Abha Meena, Stephen C. Tovey, Colin W. Taylor

J Cell Sci (2015) 128 (2): 408–420.

DOI: https://doi.org/10.1242/jcs.163071

Published: 15 January 2015

... of the drugs used. AC, adenylyl cyclase. Fig. 8. Sustained potentiation of carbachol-evoked Ca2+ signals is mediated by cAMP junctions. (A) Effects of SQ/DDA and IBMX (concentrations as in Fig. 7C) on the increase in intracellular cAMP concentration evoked by NKH477 (300 µM, 15 min). (B,C) Effects...

View article titled, Sustained signalling by PTH modulates IP 3 accumulation and IP 3 receptors through cyclic AMP junctions

Includes: Supplementary data

Journal Articles

Ca 2+ and calpain control membrane expansion during the rapid cell spreading of neutrophils

Sharon Dewitt, Robert J. Francis, Maurice B. Hallett

J Cell Sci (2013) 126 (20): 4627–4635.

DOI: https://doi.org/10.1242/jcs.124917

Published: 15 October 2013

... in neutrophils is induced by a Ca2+ signal. (A) The upper series of images show the phase contrast images and the lower series the fluo4 intensity (as a readout of Ca2+ concentration) of an individual human neutrophil undergoing cell spreading in response to f-mlp (1 µM). The graph shows the time course...

View article titled, Ca 2+ and calpain control membrane expansion during the rapid cell spreading of neutrophils

Includes: Supplementary data

Journal Articles

Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle – pivotal roles in Ca 2+ and reactive oxygen species signaling

Verónica Eisner, György Csordás, György Hajnóczky

J Cell Sci (2013) 126 (14): 2965–2978.

DOI: https://doi.org/10.1242/jcs.093609

Published: 15 July 2013

.... , Pierobon N. , Du G. G. , Sharma P. , MacLennan D. H. , Carafoli E. ( 2005 ). Ca2+ signaling in HEK-293 and skeletal muscle cells expressing recombinant ryanodine receptors harboring malignant hyperthermia and central core disease mutations. J. Biol. Chem. 280 , 15380 – 15389...

View article titled, Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle – pivotal roles in Ca 2+ and reactive oxygen species signaling

Journal Articles

During post-natal human myogenesis, normal myotube size requires TRPC1- and TRPC4-mediated Ca 2+ entry

Fabrice Antigny, Stéphane Koenig, Laurent Bernheim, Maud Frieden

J Cell Sci (2013) 126 (11): 2525–2533.

DOI: https://doi.org/10.1242/jcs.122911

Published: 1 June 2013

.... , Bernheim L. ( 2006 ). The calcineurin pathway links hyperpolarization (Kir2.1)-induced Ca2+ signals to human myoblast differentiation and fusion. Development 133 , 3107 – 3114 . 10.1242/dev.02479 Lafreniere J. F. , Mills P. , Bouchentouf M. , Tremblay J. P. ( 2006...

View article titled, During post-natal human myogenesis, normal myotube size requires TRPC1- and TRPC4-mediated Ca 2+ entry

Includes: Supplementary data

Journal Articles

`Quantal' Ca 2+ release at the cytoplasmic aspect of the Ins(1,4,5) P 3 R channel in smooth muscle

John G. McCarron, Susan Chalmers, Thomas C. Muir

J Cell Sci (2008) 121 (1): 86–98.

DOI: https://doi.org/10.1242/jcs.017541

Published: 1 January 2008

View article titled, `Quantal' Ca 2+ release at the cytoplasmic aspect of the Ins(1,4,5) P 3 R channel in smooth muscle

Journal Articles

ER vesicles and mitochondria move and communicate at synapses

Sergej L. Mironov, Natalya Symonchuk

J Cell Sci (2006) 119 (23): 4926–4934.

DOI: https://doi.org/10.1242/jcs.03254

Published: 1 December 2006

View article titled, ER vesicles and mitochondria move and communicate at synapses

Includes: Multimedia, Supplementary data

Journal Articles

Calcium signalling during excitation-contraction coupling in mammalian atrial myocytes

Martin D. Bootman, Daniel R. Higazi, Stephen Coombes, H. Llewelyn Roderick

J Cell Sci (2006) 119 (19): 3915–3925.

DOI: https://doi.org/10.1242/jcs.03223

Published: 1 October 2006

... al., 2001 ). Fig. 4. Spatially heterogeneous Ca2+ signalling during atrial myocyte EC-coupling. Panel A shows the development of a Ca2+ signal following electrical depolarisation in a single atrial myocyte. The left-hand montage shows pseudocolour-coded images of the entire cell. To indicate...

View article titled, Calcium signalling during excitation-contraction coupling in mammalian atrial myocytes

Journal Articles

In smooth muscle, FK506-binding protein modulates IP 3 receptor-evoked Ca 2+ release by mTOR and calcineurin

Debbi MacMillan, Susan Currie, Karen N. Bradley, Thomas C. Muir, John G. McCarron

J Cell Sci (2005) 118 (23): 5443–5451.

DOI: https://doi.org/10.1242/jcs.02657

Published: 1 December 2005

View article titled, In smooth muscle, FK506-binding protein modulates IP 3 receptor-evoked Ca 2+ release by mTOR and calcineurin

Journal Articles

The 12 kDa FK506-binding protein, FKBP12, modulates the Ca 2+ -flux properties of the type-3 ryanodine receptor

Kristel Van Acker, Geert Bultynck, Daniela Rossi, Vincenzo Sorrentino, Noel Boens, Ludwig Missiaen, Humbert De Smedt, Jan B. Parys, Geert Callewaert

J Cell Sci (2004) 117 (7): 1129–1137.

DOI: https://doi.org/10.1242/jcs.00948

Published: 1 March 2004

..., n =48 in the wt RyR3- and V2322D RyR3-expressing cells ( P <0.001), respectively. Rate of rise (dA/dt): 71.4±8.1, n =62 versus 107.6±11.9, n =48 in the wt RyR3- and V2322D RyR3-expressing HEK293 cells ( P <0.01), respectively. Fig. 3. Cytosolic Ca2+ signals evoked by 1 mM caffeine...

View article titled, The 12 kDa FK506-binding protein, FKBP12, modulates the Ca 2+ -flux properties of the type-3 ryanodine receptor

Journal Articles

Cyclic ADP-ribose increases Ca 2+ removal in smooth muscle

Karen N. Bradley, Susan Currie, Debbi MacMillan, Thomas C. Muir, John G. McCarron

J Cell Sci (2003) 116 (21): 4291–4306.

DOI: https://doi.org/10.1242/jcs.00713

Published: 1 November 2003

View article titled, Cyclic ADP-ribose increases Ca 2+ removal in smooth muscle

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Ca 2+ elevations disrupt interactions between intraflagellar transport and the flagella membrane in Chlamydomonas

Ca 2+ -activated cleavage of ezrin visualised dynamically in living myeloid cells during cell surface area expansion

Association of cardiac myosin-binding protein-C with the ryanodine receptor channel – putative retrograde regulation?

Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes

Mutant IP 3 receptors attenuate store-operated Ca 2+ entry by destabilizing STIM–Orai interactions in Drosophila neurons

Ca 2+ is a key factor in α-synuclein-induced neurotoxicity

Sustained signalling by PTH modulates IP 3 accumulation and IP 3 receptors through cyclic AMP junctions

Ca 2+ and calpain control membrane expansion during the rapid cell spreading of neutrophils

Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle – pivotal roles in Ca 2+ and reactive oxygen species signaling

During post-natal human myogenesis, normal myotube size requires TRPC1- and TRPC4-mediated Ca 2+ entry

`Quantal' Ca 2+ release at the cytoplasmic aspect of the Ins(1,4,5) P 3 R channel in smooth muscle

ER vesicles and mitochondria move and communicate at synapses

Calcium signalling during excitation-contraction coupling in mammalian atrial myocytes

In smooth muscle, FK506-binding protein modulates IP 3 receptor-evoked Ca 2+ release by mTOR and calcineurin

The 12 kDa FK506-binding protein, FKBP12, modulates the Ca 2+ -flux properties of the type-3 ryanodine receptor

Cyclic ADP-ribose increases Ca 2+ removal in smooth muscle

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