1-20 of 28
Keywords: COPII
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
In collection:
Membrane Trafficking
J Cell Sci (2021) 134 (17): jcs259075.
Published: 07 September 2021
... by interdependent stabilization of the cTAGE5–TANGO1 complex ( Ma and Goldberg, 2016 ; Maeda et al., 2016 ). Notably these changes in cTAGE5–TANGO1 expression at the protein level are not reflected in our RNA-seq data where, in contrast, we see significant upregulation of COPII and Golgi-related trafficking...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (17): jcs231423.
Published: 01 September 2020
... RER1, which cycles between cis-Golgi and ER, returning ER-resident proteins and unassembled subunits of multimeric complexes back to the ER. RER1 ER-Golgi Golgi-ER COPII COPI Transmembrane domain The endoplasmic reticulum (ER) is the largest membranous organelle in the eukaryotic...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (14): jcs239814.
Published: 24 July 2020
...Laura M. Westrate; Melissa J. Hoyer; Michael J. Nash; Gia K. Voeltz ABSTRACT Secretory cargo is recognized, concentrated and trafficked from endoplasmic reticulum (ER) exit sites (ERES) to the Golgi. Cargo export from the ER begins when a series of highly conserved COPII coat proteins accumulate...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (2): jcs203893.
Published: 29 January 2018
... of the COPII machinery. This article has an associated First Person interview with the first author of the paper . * Author for correspondence ( yoko.ito@riken.jp ) Competing interests The authors declare no competing or financial interests. 15 3 2017 17 8 2017 References...
Includes: Supplementary data
Journal Articles
In collection:
Imaging
J Cell Sci (2017) 130 (17): 2893–2902.
Published: 01 September 2017
...Hirohiko Iwasaki; Tomohiro Yorimitsu; Ken Sato ABSTRACT The COPII coat and the small GTPase Sar1 mediate protein export from the endoplasmic reticulum (ER) via specialized domains known as the ER exit sites. The peripheral ER protein Sec16 has been proposed to organize ER exit sites. However...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (13): 2159–2171.
Published: 01 July 2017
... (the SAR1A isoform) small GTPase. Compared to palmitoylation-deficient Wnt molecules, binding of mature Wnt to Wls increases Wls–SEC12 interaction and promotes association of Wls with SAR1, the key activator of the COPII machinery. Incorporation of Wls into this exporting ER compartment is affected by Wnt...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (19): 3597–3608.
Published: 01 October 2016
... protein required for such membrane remodeling. We show that ER-vesicle protein of 14 kD (Erv14), a cargo receptor of coat protein complex II (COPII), interacts with BMV 1a. Moreover, the perinuclear ER localization of BMV 1a is disrupted in cells lacking ERV14 or expressing dysfunctional COPII coat...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (8): 1765–1778.
Published: 15 April 2014
...David Klinkenberg; Kimberly R. Long; Kuntala Shome; Simon C. Watkins; Meir Aridor ABSTRACT The inner and outer layers of COPII mediate cargo sorting and vesicle biogenesis. Sec16A and p125A (officially known as SEC23IP) proteins interact with both layers to control coat activity, yet the steps...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (2): 376–387.
Published: 15 January 2014
...-to-Golgi transport is crucial for maintaining the different membrane lipid composition and identities of organelles. Despite their importance, mechanisms regulating transport remain elusive. Here we report that in yeast coat protein complex II (COPII) vesicle-mediated transport of ceramide from the ER...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (10): 2151–2156.
Published: 15 May 2013
... residues in the N-terminus of the protein. Here, we describe the effects of Chs2p phosphorylation on the interaction with coat protein complex II (COPII). Identification of a cdc5 ts mutant, which fails to transport Chs2p–3xGFP to the bud-neck and instead accumulates the protein in intracellular puncta...
Journal Articles
J Cell Sci (2012) 125 (14): 3412–3420.
Published: 15 July 2012
... expanded ER sheets and the plasma membrane. * These authors contributed equally to this work ‡ Author for correspondence ( kkurokawa@riken.jp ) 19 2 2012 © 2012. Published by The Company of Biologists Ltd 2012 ERES COPII ER membrane curvature The secretory pathway...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (3): 673–684.
Published: 01 February 2012
...Anna K. Townley; Katy Schmidt; Lorna Hodgson; David J. Stephens Epithelial morphogenesis is directed by interactions with the underlying extracellular matrix. Secretion of collagen and other matrix components requires efficient coat complex II (COPII) vesicle formation at the endoplasmic reticulum...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (23): 4032–4038.
Published: 01 December 2010
...Helen Hughes; David J. Stephens Mitotic inhibition of COPII-dependent export of proteins from the endoplasmic reticulum results in disassembly of the Golgi complex. This ensures ordered inheritance of organelles by the two daughter cells. Reassembly of the Golgi is intimately linked to the re...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2010) 123 (10): 1705–1715.
Published: 15 May 2010
...Carine Bonnon; Markus W. Wendeler; Jean-Pierre Paccaud; Hans-Peter Hauri Selective export of transmembrane proteins from the endoplasmic reticulum (ER) relies on recognition of cytosolic-domain-localized transport signals by the Sec24 subunit of the COPII vesicle coat. Human cells express four...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (16): 2924–2934.
Published: 15 August 2009
...Helen Hughes; Annika Budnik; Katy Schmidt; Krysten J. Palmer; Judith Mantell; Chris Noakes; Andrew Johnson; Deborah A. Carter; Paul Verkade; Peter Watson; David J. Stephens The COPII complex mediates the selective incorporation of secretory cargo and relevant machinery into budding vesicles...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2009) 122 (10): 1680–1690.
Published: 15 May 2009
... of nocodazole to induce additional proliferation of ER exit sites in syntaxin-18-depleted cells may reflect a shortage of cycling components required for COPII assembly, which may be due to the inhibition of retrograde transport to the ER. To test this idea, we focused attention on the distribution of ERGIC-53...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (18): 3025–3034.
Published: 15 September 2008
...Anna K. Townley; Yi Feng; Katy Schmidt; Deborah A. Carter; Robert Porter; Paul Verkade; David J. Stephens The COPII coat assembles on endoplasmic reticulum membranes to coordinate the collection of secretory cargo with the formation of transport vesicles. During COPII assembly, Sar1 deforms...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (6): 865–876.
Published: 15 March 2008
... sorting to ERESs to be a slow and diffusion-unlimited process. Our findings exclude COPI, and identify the COPII protein complex to be directly involved in the secretory cargo sorting and redistribution functions of ERESs. * Author for correspondence (e-mail: koty@post.tau.ac.il ) 11 12...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2006) 119 (22): 4730–4740.
Published: 15 November 2006
...Leah M. Welsh; Amy Hin Yan Tong; Charles Boone; Ole N. Jensen; Stefan Otte Erv41p and Erv46p are integral membrane proteins conserved across species. They were originally identified as abundant constituents of COPII-coated vesicles, and form a complex which cycles between the endoplasmic reticulum...
Journal Articles
J Cell Sci (2006) 119 (11): 2173–2183.
Published: 01 June 2006
... carriers from stationary ERGIC-53-positive membranes, however, suggest a stable compartment model in which ER-derived cargo is first shuttled from ER-exit sites to stationary ERGIC clusters in a COPII-dependent step and subsequently to the Golgi in a second vesicular transport step. This model can better...