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Keywords: CK1α
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Journal Articles
CK1α protects WAVE from degradation to regulate cell shape and motility in the immune response
Open Access
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (23): jcs258891.
Published: 9 December 2021
... phosphorylation. However, the in vivo relevance of the phosphorylation of WAVE proteins remains largely unknown. Here, we identified casein kinase I alpha (CK1α) as a regulator of WAVE, thereby controlling cell shape and cell motility in Drosophila macrophages. CK1α binds and phosphorylates WAVE in vitro...
Includes: Supplementary data
