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Keywords: CI-MPR
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Journal Articles
Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting
Journal:
Journal of Cell Science
J Cell Sci (2020) 133 (15): jcs246033.
Published: 3 August 2020
... the glucose transporter GLUT1 (also known as SLC2A1). The role of retromer in the retrograde sorting of the cation-independent mannose 6-phosphate receptor (CI-MPR, also known as IGF2R) from endosomes back to the trans -Golgi network remains controversial. Here, by applying knocksideways technology, we...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2007) 120 (1): 45–54.
Published: 1 January 2007
... Endosome CI-MPR TGN Sorting nexin Retromer In mammalian cells, there are two distinct mannose-6-phosphate receptors (MPRs) - the cation-dependent and cation-independent MPRs (CD-MPR and CI-MPR, respectively) ( Ghosh et al., 2003 ). These receptors function by associating with the mannose-6...
Includes: Multimedia, Supplementary data
Journal Articles
Jez G. Carlton, Miriam V. Bujny, Brian J. Peter, Viola M. J. Oorschot, Anna Rutherford, Rebecca S. Arkell, Judith Klumperman, Harvey T. McMahon, Peter J. Cullen
Journal:
Journal of Cell Science
J Cell Sci (2005) 118 (19): 4527–4539.
Published: 1 October 2005
... Limited 2005 2005 Sorting nexin Retromer CI-MPR Phosphoinositide PX-domain The endosomal system functions as an internal membraneous network designed to sort internalised cargo to appropriate subcellular destinations. Molecules internalised at the cell surface are initially delivered...