...Lisa te Molder; Juri Juksar; Rolf Harkes; Wei Wang; Maaike Kreft; Arnoud Sonnenberg ABSTRACT Tetraspanin CD151 has been suggested to regulate cell adhesion through its association with laminin-binding integrins α3β1 and α6β4; however, its precise function in keratinocyte adhesion remains elusive...

...Rafal Sadej; Xiaohong Lu; Lukasz Turczyk; Vera Novitskaya; Andrea F. Lopez-Clavijo; Radzisław Kordek; Piotr Potemski; Michael J. O. Wakelam; Hanna Romanska-Knight; Fedor Berditchevski ABSTRACT Expression of the tetraspanin CD151 is frequently upregulated in epithelial malignancies and correlates...

...Xiuwei H. Yang; Rossen Mirchev; Xinyu Deng; Patrick Yacono; Helen L. Yang; David E. Golan; Martin E. Hemler Laminin-binding integrins (α3β1, α6β1, α6β4, α7β1) are almost always expressed together with tetraspanin CD151. In every coexpressing cell analyzed to date, CD151 makes a fundamental...

...Jessica L. Johnson; Nicole Winterwood; Kris A. DeMali; Christopher S. Stipp Tetraspanins regulate integrin-dependent tumor cell interactions with the extracellular matrix. Here we show that tetraspanin CD151, which plays critical roles in regulating the adhesion and motility of individual tumor...

..., human gamete fusion remains largely unknown. We now show that an anti-α6 integrin mAb (GoH3) strongly inhibited human sperm-egg fusion in human zona-free eggs. Furthermore, a mAb directed against CD151, a tetraspanin known to associate with α6β1, partially inhibited sperm-egg fusion. By contrast...