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Keywords: CCAN
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Journal Articles

CENP-C-targeted PLK-1 regulates kinetochore function in C. elegans embryos

In collection:
Cell cycle
Laura Bel Borja, Samuel J. P. Taylor, Flavie Soubigou, Federico Pelisch
Journal: Journal of Cell Science
J Cell Sci (2024) 137 (22): jcs262327.
https://doi.org/10.1242/jcs.262327
Published: 28 November 2024
... assembly, spindle assembly checkpoint (SAC) activation, chromosome segregation and cytokinesis. BUB-1 targets PLK-1 to the outer kinetochore and, in mammals, the inner kinetochore PLK1 targeting is mediated by the constitutive centromere associated network (CCAN). BUB-1-targeted PLK-1 plays a key role...
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Includes: Supplementary data
Journal Articles

Kinetochores accelerate centrosome separation to ensure faithful chromosome segregation

Nunu Mchedlishvili, Samuel Wieser, René Holtackers, Julien Mouysset, Mukta Belwal, Ana C. Amaro, Patrick Meraldi
Journal: Journal of Cell Science
J Cell Sci (2012) 125 (4): 906–918.
https://doi.org/10.1242/jcs.091967
Published: 15 February 2012
... checkpoint . J. Cell Biol. 161 , 281 - 294 . Hori T. , Amano M. , Suzuki A. , Backer C. B. , Welburn J. P. , Dong Y. , McEwen B. F. , Shang W. H. , Suzuki E. , Okawa K. , et al . ( 2008 ). CCAN makes multiple contacts with centromeric DNA...
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Includes: Multimedia, Supplementary data