1-20 of 56
Keywords: C. elegans
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci jcs.258818.
Published: 17 December 2021
...-subunit SMC complex that binds to and compacts chromosomes. Here we addressed the regulation of condensin binding dynamics using C. elegans condensin DC, which represses X chromosomes in hermaphrodites for d osage c ompensation. We established fluorescence recovery after photobleaching (FRAP) using...
Journal Articles
J Cell Sci (2021) 134 (24): jcs259085.
Published: 15 December 2021
... organization during recycling remain unclear. In this study, we identified a synergistic endosomal actin assembly restricting mechanism in C. elegans involving WTS-1, the homolog of LATS kinases, which is a core component of the Hippo pathway. WTS-1 resides on the sorting endosomes and colocalizes...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (23): jcs259088.
Published: 02 December 2021
... defined by the histone variant CENP-A. In the holocentric nematode C. elegans , CENP-A deposition depends on the loading factor KNL-2. Depletion of either CENP-A or KNL-2 results in defects in centromere maintenance, chromosome condensation and kinetochore formation, leading to chromosome segregation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (22): jcs258834.
Published: 15 November 2021
...Simona Abbatemarco; Alexandra Bondaz; Francoise Schwager; Jing Wang; Christopher M. Hammell; Monica Gotta ABSTRACT When exposed to stressful conditions, eukaryotic cells respond by inducing the formation of cytoplasmic ribonucleoprotein complexes called stress granules. Here, we use C. elegans...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (17): jcs258456.
Published: 03 September 2021
... permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Highlighted Article: Tagged endogenous C. elegans MPK-1 shows activation-dependent cytosol-to-nuclear translocation. This tool provides novel insights into MPK-1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (14): jcs253088.
Published: 26 July 2021
... levels is critical. In Caenorhabditis elegans , the anaphase-promoting complex/cyclosome and its co-activator FZR-1 (APC/C FZR-1 ), a ubiquitin ligase, negatively regulates centrosome assembly through SAS-5 degradation. In this study, we report the C. elegans ZYG-1 (Plk4 in humans) as a potential...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (21): jcs246793.
Published: 03 November 2020
...Chunxia Wang; Yuyan Yang; Rong Fu; Yi Zhu; Huimin Zhang ABSTRACT Periodic pattern formation on the cellular and tissue scale is an important process and has been extensively studied. However, periodic pattern formation at the subcellular level still remains poorly understood. The C. elegans...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (19): jcs231357.
Published: 09 October 2019
... forces during cytokinesis is not well understood. Here we show that, under mechanical stress, cortical actomyosin flow can switch polarization during cytokinesis in the C. elegans embryo. In unstressed embryos, longitudinal cortical flow contributes to contractile ring formation, while rotational...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (19): jcs234195.
Published: 01 October 2019
... autophagy caused by accumulation of non-degradative autolysosomes, but very little is known about the mechanism underlying this cellular phenotype. Here, we demonstrate that loss of function of the RBG-1–RBG-2 complex ameliorates the autophagy defect in C. elegans epg-5 mutants. The suppression effect...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (14): jcs230714.
Published: 15 July 2019
...Nisha Hirani; Rukshala Illukkumbura; Tom Bland; Grégoire Mathonnet; Delphine Suhner; Anne-Cecile Reymann; Nathan W. Goehring ABSTRACT The association of molecules within membrane microdomains is critical for the intracellular organization of cells. During polarization of the C. elegans zygote, both...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (5): jcs227660.
Published: 28 February 2019
... in the plasma membrane and regulates endocytic transport. Despite these important functions, the structure–function relationship of this protein is poorly understood. Taking advantage of the tat-1 mutations identified by the C. elegans million mutation project, we investigated the effects of 16 single amino...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (22): jcs219956.
Published: 21 November 2018
... . 10.15252/embj.201487943 Cooper , J. F. , Dues , D. J. , Spielbauer , K. K. , Machiela , E. , Senchuk , M. M. and Van Raamsdonk , J. M. ( 2015 ). Delaying aging is neuroprotective in Parkinson's disease: a genetic analysis in C. elegans models . NPJ Parkinsons Dis.   1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (20): jcs223107.
Published: 22 October 2018
... Bertrand , V. and Hobert , O. ( 2009 ). Linking asymmetric cell division to the terminal differentiation program of postmitotic neurons in C. elegans . Dev. Cell   16 , 563 - 575 . 10.1016/j.devcel.2009.02.011 Bobinnec , Y. , Fukuda , M. and Nishida , E. ( 2000...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (11): jcs214379.
Published: 11 June 2018
... are regulated at the post-transcriptional level is poorly understood. Caenorhabditis elegans hemidesmosomes (CeHDs) have a similar structure and composition to their mammalian counterparts, making C. elegans an ideal model for studying hemidesmosomes. Here, we focus on the transcription regulator CCAR-1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (24): 4200–4212.
Published: 15 December 2017
.... ( 2006 ). Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans . Dev. Biol.   299 , 386 - 397 . 10.1016/j.ydbio.2006.08.002 Balla , T. and Varnai , P. ( 2009 ). Visualization of cellular phosphoinositide pools with GFP...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (23): 4063–4071.
Published: 01 December 2017
... declare no competing or financial interests. 6 2 2017 23 10 2017 © 2017. Published by The Company of Biologists Ltd 2017 http://www.biologists.com/user-licence-1-1/ Summary: Dynein and EFF-1 have a non-autonomous function in patterning PVD dendrites in C. elegans through...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (23): 3965–3974.
Published: 01 December 2017
... for future research efforts aimed at elucidating its roles in neuronal and non-neuronal tissues. Given the identification of srGAPs as modulators of cadherin-dependent cell–cell adhesion in the C. elegans embryo ( Zaidel-Bar et al., 2010 ) and in vertebrate tissue culture ( Liang et al., 2017...
Journal Articles
J Cell Sci (2017) 130 (15): 2631–2643.
Published: 01 August 2017
...-factor, pyrroloquinoline quinone (PQQ), activates the C. elegans DUOX protein BLI-3 to produce the ROS H 2 O 2 at the plasma membrane, which is subsequently degraded by peroxidase (MLT-7), eventually ensuring adequate levels of ROS. These ROS signals are transduced mainly by the oxidative stress...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (9): 1652–1661.
Published: 01 May 2017
... substitutions and depletion owing to RNAi, we demonstrate that different combinations of tubulin isotypes confer distinct properties to microtubule dynamics and mitotic spindle oscillation in C. elegans embryos. Tubulin isotypes Microtubules C. elegans Microtubules (MTs) are dynamic polymers...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (7): 1224–1231.
Published: 01 April 2017
... © 2017. Published by The Company of Biologists Ltd 2017 Summary: Upon reduction of N-glycosylation, E-cadherin is not efficiently localized in the cell–cell contact site contributing to adhesion defects in the two-cell C. elegans embryo. This phenotype is rescued by concomitant loss...
Includes: Supplementary data