1-4 of 4
Keywords: Brca2
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci (2015) 128 (4): 717–727.
Published: 15 February 2015
... that the recombination mediator Brca2 associates with lamin and the cohesion factor Pds5 to secure persistent recombination sites at the nuclear envelope. In Rad51 −/− females, all persistent DNA breaks are directed to the nuclear envelope. By contrast, a reduction of Pds5 or Brca2 levels abolishes the movement and has...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (22): 5555–5563.
Published: 15 November 2012
... melanogaster Chk2 (a downstream kinase that initiates the meiotic checkpoint) rescues the cycG mutant eggshell phenotype. In vivo , CycG associates with Rad9 and BRCA2. These two proteins are components of the 9-1-1 complex, which is involved in sensing DSBs and in activating meiotic checkpoint control...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (9): 1395–1400.
Published: 1 May 2010
...Sergey Lekomtsev; Julien Guizetti; Andrei Pozniakovsky; Daniel W. Gerlich; Mark Petronczki Germline mutations in the tumor-suppressor gene BRCA2 predispose to breast and ovarian cancer. BRCA2 plays a well-established role in maintaining genome stability by regulating homologous recombination. BRCA2...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2010) 123 (7): 1124–1130.
Published: 1 April 2010
...Tomohiro Hayakawa; Fan Zhang; Noriyo Hayakawa; Yasuko Ohtani; Kaori Shinmyozu; Jun-ichi Nakayama; Paul R. Andreassen PALB2 physically and functionally connects the proteins encoded by the BRCA1 and BRCA2 breast and ovarian cancer genes into a DNA-damage-response network. However, it remains unclear...
Includes: Supplementary data