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Keywords: Bone resorption
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J Cell Sci (2017) 130 (12): 2026–2035.
Published: 15 June 2017
.... Osteoclast Bone resorption Pit resorption Trench resorption Intermittent resorption Continuous resorption Vejle Hospital Lillebaelt Hospital A functional osteoclast (OC) must be able to resorb bone matrix, but also to move its resorptive activity over the bone surface...
Includes: Supplementary data
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J Cell Sci (2009) 122 (1): 136–144.
Published: 1 January 2009
... of PKC to the basolateral membrane domain of osteoclasts, an aspect of spatiotemporal signaling not previously recognized. * Author for correspondence (e-mail: [email protected] ) 27 9 2008 © The Company of Biologists Limited 2009 2009 Bone resorption Cytosolic Ca 2...
Includes: Multimedia, Supplementary data
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J Cell Sci (2000) 113 (13): 2445–2453.
Published: 1 July 2000
... by Company of Biologists 2000 RANKL Osteoclast TGF β Bone resorption Bone matrix The osteoclast is the cell that resorbs bone. Excessive activity by this cell is responsible for the bone loss that causes osteoporosis and other diseases of clinical importance. It has been known for some...
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J Cell Sci (1997) 110 (5): 589–596.
Published: 1 March 1997
...Takuya Sato; Maria del Carmen Ovejero; Peng Hou; Anne-Marie Heegaard; Masayoshi Kumegawa; Niels Tækker Foged; Jean-Marie Delaissé ABSTRACT The osteoclasts are the cells responsible for bone resorption. Matrix metalloproteinases (MMPs) appear crucial for this process. To identify possible MMP...
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J Cell Sci (1995) 108 (12): 3649–3659.
Published: 1 December 1995
...L. Blavier; J. M. Delaissé ABSTRACT A key event in bone resorption is the recruitment of osteoclasts to future resorption sites. We follow here the migration of preosteoclasts from the periosteum to the developing marrow cavity of fetal mouse metatarsals in culture, and investigate the role...
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J Cell Sci (1995) 108 (6): 2221–2230.
Published: 1 June 1995
... by osteoclasts, collagenase (matrix metalloproteinase-1, EC 3.4.24.7) is also required for osteoclastic bone resorption, and may be directly involved in collagen degradation in the hemivacuole. We assessed the effects of inhibitors of cysteine proteinases and collagenase on bone resorption by osteoclasts...
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J Cell Sci (1994) 107 (2): 517–526.
Published: 1 February 1994
... motility and ion transport are regulated by separate G protein-coupled pathways. * Author for correspondence 21 06 1993 19 10 1993 © 1994 by Company of Biologists 1994 G protein K + channel pseudopod bone resorption motility GTP-binding proteins (G proteins...
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J Cell Sci (1992) 101 (3): 681–686.
Published: 1 March 1992
...) pathological bone resorption, a specific interaction with stromal cells being necessary for the latter to occur. TIM-mediated bone resorption could account for different clinical and pathological patterns of tumour osteolysis. * Author for correspondence 21 10 1991 11 12 1991 © 1992...
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J Cell Sci (1985) 76 (1): 155–165.
Published: 1 June 1985
...T. J. Chambers; K. Fuller ABSTRACT The cell-free endocranial surface of young adult rat parietal bones was used as a substrate for osteoclastic bone resorption, either without prior treatment, or after incubation of the parietal bones with collagenase or neonatal rat calvarial cells. Untreated...