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1-2 of 2
Keywords: Blood pressure
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Journal Articles
Motoko Chiga, Fatema H. Rafiqi, Dario R. Alessi, Eisei Sohara, Akihito Ohta, Tatemitsu Rai, Sei Sasaki, Shinichi Uchida
Journal:
Journal of Cell Science
J Cell Sci (2011) 124 (9): 1391–1395.
Published: 1 May 2011
... that NCC phosphorylation was almost completely abolished in Wnk4 D561A/+ Spak T 243A/T243A Osr1 T185A/+ triple knock-in mice, clearly demonstrating that NCC phosphorylation in vivo is dependent on the WNK-OSR1/SPAK cascade. In addition, the high blood pressure, hyperkalemia and metabolic acidosis observed...
Journal Articles
Ciaran Richardson, Kei Sakamoto, Paola de los Heros, Maria Deak, David G. Campbell, Alan R. Prescott, Dario R. Alessi
Journal:
Journal of Cell Science
J Cell Sci (2011) 124 (5): 789–800.
Published: 1 March 2011
... suppress the activity of both NCC and NKCC2. * Authors for correspondence ( d.r.alessi@dundee.ac.uk ; c.j.z.richardson@dundee.ac.uk ) 20 10 2010 © 2011. 2011 AMPK Blood pressure NCC NKCC2 SPAK-OSR1 WNK SPAK (for ‘STE20-and-SPS1-related proline and alanine-rich kinase...
Includes: Supplementary data
