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Keywords: Biophysics
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Lipid biology
J Cell Sci (2022) 135 (15): jcs259704.
Published: 3 August 2022
.... Here, cellular Cl − efflux assays and immunofluorescence microscopy studies have identified intracellular Zn 2+ release as the trigger for CLIC1 activation and membrane insertion. Biophysical assays confirmed specific binding to Zn 2+ , inducing membrane association and enhancing Cl − efflux in a pH...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (24): jcs255562.
Published: 24 December 2020
..., which forms an ion channel in primary cilia and endoplasmic reticulum (ER) membranes of renal collecting duct cells. Elevated internal Ca 2+ modulates polycystin-2 voltage-dependent gating and subsequent desensitization – two biophysical regulatory mechanisms that control its function at physiological...
Includes: Supplementary data
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Cytoskeleton
J Cell Sci (2020) 133 (8): jcs232983.
Published: 24 April 2020
... and chick neurites using time-lapse imaging, fluorescent speckle microscopy, super-resolution imaging and biophysical analysis. Pharmacologically inhibiting either dynein activity or MT assembly reduced neurite elongation rates as well as bulk and individual MT anterograde translocation. Simultaneously...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (5): jcs241075.
Published: 10 March 2020
... biophysical aspects and focus on three key principles – rearrangement and destabilization of the plasma membrane and the cytoskeleton, alterations and disassembly of the nuclear envelope, and chromatin decondensation as a driving force of intracellular reorganization. * Authors for correspondence...
Journal Articles
J Cell Sci (2006) 119 (1): 66–74.
Published: 1 January 2006
... and biophysical properties of the binding interactions between cadherins expressed on the surface of living cells, at the single-molecule level. Single-molecule force spectroscopy reveals that classical cadherins, N-cadherin and E-cadherin, form bonds that display adhesion specificity, and a pronounced difference...
Journal Articles