...-opted by the non-ciliated T cell to orchestrate polarized endosome recycling and to sustain signaling during immune synapse formation. Here, we investigated the potential role of Bardet–Biedl syndrome 1 protein (BBS1), an essential core component of the BBS complex that cooperates with the IFT system...

..., which alone was sufficient to rescue olfactory function. Olfactory cilia Bardet–Biedl syndrome Peripheral olfactory system Intraflagellar transport Basal body Gene therapy Bardet–Beidl syndrome (BBS) is a ciliopathy in which symptoms manifest from disruptions in ciliary growth...

... no competing interests. 4 03 2013 17 03 2014 © 2014. Published by The Company of Biologists Ltd 2014 Alstrom Syndrome Bardet-Biedl Syndrome Notch Basal body Cilia Endosomal sorting Proteins associated with primary cilia and their anchoring basal bodies play a variety...

... polypeptides. Here we show that MKKS/BBS6, one of several proteins associated with Bardet-Biedl syndrome (BBS), is a Group II chaperonin-like protein that has evolved recently in animals from a subunit of the eukaryotic chaperonin CCT/TRiC, and diverged rapidly to acquire distinct functions. Unlike other...